{"id":267,"title":"Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion","short_name":"Uncoupling of OXPHOS leading to growth inhibition 5","created_at":"2018-06-12T04:23:10.000-04:00","updated_at":"2023-04-29T16:03:01.000-04:00","corresponding_author":{"id":322,"created_at":"2016-06-30T07:13:47.000-04:00","updated_at":"2026-05-15T09:06:58.000-04:00","subscribed":true,"novice":true},"aop_stressors":[],"aop_mies":[{"event_id":1446,"event":"Decrease, Coupling of oxidative phosphorylation","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":2070,"event":"Increase, Glycolysis","event_type":"KeyEvent"},{"event_id":2071,"event":"Decrease, Glucose pool","event_type":"KeyEvent"},{"event_id":1821,"event":"Decrease, Cell proliferation","event_type":"KeyEvent"}],"aop_aos":[{"event_id":1521,"event":"Decrease, Growth","event_type":"AdverseOutcome"}],"relationships":[{"relation":3266,"upstream_event_id":1446,"upstream_event":"Decrease, Coupling of oxidative phosphorylation","downstream_event_id":2070,"downstream_event":"Increase, Glycolysis"},{"relation":3267,"upstream_event_id":2070,"upstream_event":"Increase, Glycolysis","downstream_event_id":2071,"downstream_event":"Decrease, Glucose pool"},{"relation":3268,"upstream_event_id":2071,"upstream_event":"Decrease, Glucose pool","downstream_event_id":1821,"downstream_event":"Decrease, Cell proliferation"},{"relation":3269,"upstream_event_id":1821,"upstream_event":"Decrease, Cell proliferation","downstream_event_id":1521,"downstream_event":"Decrease, Growth"}]}