{"id":489,"title":"Inhibition of voltage-gated sodium channels leading to decreased cognition","short_name":"Voltage-gated sodium channels and DNT","created_at":"2023-02-22T08:31:03.000-05:00","updated_at":"2026-03-25T13:52:44.000-04:00","corresponding_author":{"id":19508,"created_at":"2024-12-16T10:23:25.000-05:00","updated_at":"2026-06-12T07:48:41.000-04:00","subscribed":true,"novice":true},"aop_stressors":[{"stressor_id":762,"stressor_name":" Deltamethrin"}],"aop_mies":[{"event_id":1353,"event":"Binding to voltage-gated sodium channel","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":1977,"event":"Disruption of sodium channel gating kinetics","event_type":"KeyEvent"},{"event_id":2116,"event":"Decreased, oligodendrocyte differentiation","event_type":"KeyEvent"},{"event_id":2107,"event":"Hypomyelination","event_type":"KeyEvent"},{"event_id":2108,"event":"Altered, white brain matter","event_type":"KeyEvent"}],"aop_aos":[{"event_id":402,"event":"Cognitive function, decreased ","event_type":"AdverseOutcome"}],"relationships":[]}