<?xml version="1.0" encoding="UTF-8"?>
<data xmlns="http://www.aopkb.org/aop-xml">
  <aop id="d7c38990-a743-4cd4-b91c-0d554c3b3c5b">
    <title>Excessive reactive oxygen species leading to growth inhibition via protein oxidation and reduced cell growth</title>
    <short-name>ROS leading to growth inhibition via protein oxidation and reduced cell growth</short-name>
    <point-of-contact>You Song</point-of-contact>
    <authors></authors>
    <coaches>
      <coach>Shihori Tanabe</coach>
    </coaches>
    <external_links>
    </external_links>
    <status>
      <wiki-license>BY-SA</wiki-license>
    </status>
    <oecd-project/>
    <handbook-version>2.7</handbook-version>
    <abstract></abstract>
    <applicability>
    </applicability>
    <overall-assessment>
      <description></description>
      <applicability></applicability>
      <key-event-essentiality-summary></key-event-essentiality-summary>
      <weight-of-evidence-summary></weight-of-evidence-summary>
      <known-modulating-factors>&lt;div&gt;
&lt;table class="table table-bordered table-fullwidth"&gt;
	&lt;thead&gt;
		&lt;tr&gt;
			&lt;th&gt;Modulating Factor (MF)&lt;/th&gt;
			&lt;th&gt;Influence or Outcome&lt;/th&gt;
			&lt;th&gt;KER(s) involved&lt;/th&gt;
		&lt;/tr&gt;
	&lt;/thead&gt;
	&lt;tbody&gt;
		&lt;tr&gt;
			&lt;td&gt;&amp;nbsp;&lt;/td&gt;
			&lt;td&gt;&amp;nbsp;&lt;/td&gt;
			&lt;td&gt;&amp;nbsp;&lt;/td&gt;
		&lt;/tr&gt;
	&lt;/tbody&gt;
&lt;/table&gt;
&lt;/div&gt;
</known-modulating-factors>
      <quantitative-considerations></quantitative-considerations>
    </overall-assessment>
    <potential-applications></potential-applications>
    <references></references>
    <source>AOPWiki</source>
    <creation-timestamp>2025-09-08T04:10:24</creation-timestamp>
    <last-modification-timestamp>2025-09-09T03:08:57</last-modification-timestamp>
  </aop>
  <vendor-specific id="525a9c80-9b67-4723-bd27-47a72c7f406c" name="AopWiki" version="2026-04-18 19:50:10 +0000">
    <aop-reference id="d7c38990-a743-4cd4-b91c-0d554c3b3c5b" aop-wiki-id="597"/>
  </vendor-specific>
</data>
