{"id":659,"title":"Renal tubular epithelial injury leading to renal interstitial fibrosis via maladaptive repair","short_name":"Renal tubular injury to fibrosis via maladaptive repair","created_at":"2026-11-08T16:45:42.000-05:00","updated_at":"2026-11-09T02:37:02.000-05:00","corresponding_author":{"id":21289,"created_at":"2026-10-16T02:02:38.000-04:00","updated_at":"2026-11-09T21:09:15.000-05:00","subscribed":true,"novice":true},"aop_stressors":[],"aop_mies":[],"aop_kes":[{"event_id":2465,"event":"Increase, renal tubular epithelial cell injury","event_type":"KeyEvent"},{"event_id":2464,"event":"Increase, tubular epithelial cells exhibiting a failed-repair phenotype","event_type":"KeyEvent"}],"aop_aos":[{"event_id":2404,"event":"Increase, kidney fibrosis","event_type":"AdverseOutcome"}],"relationships":[{"relation":5102,"upstream_event_id":2465,"upstream_event":"Increase, renal tubular epithelial cell injury","downstream_event_id":2464,"downstream_event":"Increase, tubular epithelial cells exhibiting a failed-repair phenotype"},{"relation":5103,"upstream_event_id":2464,"upstream_event":"Increase, tubular epithelial cells exhibiting a failed-repair phenotype","downstream_event_id":2404,"downstream_event":"Increase, kidney fibrosis"}]}