CHEBI:17347 CHEBI testosterone CL:0000019 CL sperm D005298 MESH fertility CHEBI:24261 CHEBI glucocorticoid PR:000011406 PR glucocorticoid receptor GO:0006915 GO apoptotic process VT:0002673 VT sperm quantity GO:0006704 GO glucocorticoid biosynthetic process GO:0001775 GO cell activation GO:0004883 GO glucocorticoid receptor activity GO:0050810 GO regulation of steroid biosynthetic process 2 WIKI decreased 1 WIKI increased 8 WIKI morphological change 4 WIKI abnormal 10116 NCBI Rattus norvegicus 9606 NCBI Homo sapiens Apoptosis of adult Leydig cells, Decreased testosterone by adult Leydig cells Cellular CL:0000178 CL Leydig cell AOPWiki 2016-11-29T18:41:25 2017-09-16T10:15:32 Decreased sperm quantity or quality in the adult, Decreased fertility Individual AOPWiki 2016-11-29T18:41:25 2016-12-03T16:37:50 Stimulation of adult Leydig cells via the Adrenal Corticosterone, Increased Glucocorticoid Molecular AOPWiki 2016-11-29T18:41:26 2016-12-03T16:37:51 Glucocorticoid Receptor mediated alterations in steriodogenic enzymes, Decreased testostero Cellular AOPWiki 2016-11-29T18:41:26 2016-12-03T16:37:51 Direct effects of Corticosterone on steroidogenesis, Decreased testosterone by adult Leydig Cellular AOPWiki 2016-11-29T18:41:26 2016-12-03T16:37:51 Decreased Adult Testosterone 2 <p>Gary Klinefelter and Susan Laws</p> BY-SA 1.0 High Male High Adult, reproductively mature High High AOPWiki 2016-11-29T18:41:16 2026-01-11T16:56:06