AOPs

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Showing 26 to 50 of 594 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
182 Weather event contributes abnormal foraging leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
171 Chronic cytotoxicity of the serous membrane leading to pleural/peritoneal mesotheliomas in the rat. Charles Wood BY-SA None 1090: Increased, mesotheliomas
175 Thyroperoxidase inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 279: Thyroperoxidase, Inhibition 1101: Altered, Amphibian metamorphosis
176 Sodium Iodide Symporter (NIS) Inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 424: Inhibition, Na+/I- symporter (NIS) 1101: Altered, Amphibian metamorphosis
177 Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality Kellie Fay BY-SA 1103: Inhibition, Cyclooxygenase 1 activity
178 Nicotinic acetylcholine receptor activation contributes to mitochondrial dysfunction and leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
179 Varroa mite infestation increases virus levels leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
180 Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
181 Weather event contributes to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
90 Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2 Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor
73 Xenobiotic Inhibition of Dopamine-beta-Hydroxylase and subsequent reduced fecundity Undefined BY-SA 526: Inhibition, Inhibition of Dopamine-beta-hydroxylase 527: Decreased, Decreased fecundity
74 Modulation of Adult Leydig Cell Function Subsequent to Hypermethylation in the Fetal Testis Undefined BY-SA 662: Decreased testosterone by the fetal Leydig cells, Hypermethylation in the fetal testis 543: Decreased fertility in the adult, Decreased sperm quantity and/or quality in the adult testis
77 Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
78 Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1 Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor
79 Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
80 Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor
81 Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure Carlie LaLone BY-SA None
82 Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure Carlie LaLone BY-SA None
84 Suppression of immune system contributes to impaired development and leads to colony loss/failure Carlie LaLone BY-SA None
85 Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure Carlie LaLone BY-SA None
86 Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure Carlie LaLone BY-SA None
87 Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
88 Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
89 Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
72 Epigenetic modification of PPARG leading to adipogenesis Michelle Angrish BY-SA 1447: obesity