AOPs

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Showing 401 to 425 of 558 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
340 DNA methyltransferase inhibition leading to transgenerational effects (1) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
339 DNA methyltransferase inhibition leading to population decline (4) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
337 DNA methyltransferase inhibition leading to population decline (2) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
336 DNA methyltransferase inhibition leading to population decline (1) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
299 Deposition of energy leading to population decline via DNA oxidation and follicular atresia You Song BY-SA 1686: Deposition of Energy
291 Mitochondrial ATP synthase antagonism leading to growth inhibition (2) You Song BY-SA 1785: Increase, Mitochondrial ATP synthase antagonism 1521: Decrease, Growth
290 Mitochondrial ATP synthase antagonism leading to growth inhibition (1) You Song BY-SA 1785: Increase, Mitochondrial ATP synthase antagonism 1521: Decrease, Growth
287 Mitochondrial complex III antagonism leading to growth inhibition (2) You Song BY-SA 1542: Inhibition, Mitochondrial complex III 1521: Decrease, Growth
286 Mitochondrial complex III antagonism leading to growth inhibition (1) You Song BY-SA 1542: Inhibition, Mitochondrial complex III 1521: Decrease, Growth
263 Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation You Song BY-SA 1446: Decrease, Coupling of oxidative phosphorylation 1521: Decrease, Growth WPHA/WNT Endorsed 1.92
264 Uncoupling of oxidative phosphorylation leading to growth inhibition via ATP depletion associated cell death You Song BY-SA 1446: Decrease, Coupling of oxidative phosphorylation 1521: Decrease, Growth Under Development 1.92
265 Uncoupling of oxidative phosphorylation leading to growth inhibition via increased cytosolic calcium You Song BY-SA 1446: Decrease, Coupling of oxidative phosphorylation 1521: Decrease, Growth Under Development 1.92
266 Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased Na-K ATPase activity You Song BY-SA 1446: Decrease, Coupling of oxidative phosphorylation 1521: Decrease, Growth Under Development 1.92
267 Uncoupling of oxidative phosphorylation leading to growth inhibition via glucose depletion You Song BY-SA 1446: Decrease, Coupling of oxidative phosphorylation 1521: Decrease, Growth Under Development 1.92
268 Uncoupling of oxidative phosphorylation leading to growth inhibition via mitochondrial swelling You Song BY-SA 1446: Decrease, Coupling of oxidative phosphorylation 1521: Decrease, Growth Under Development 1.92
311 Deposition of energy leading to population decline via DNA oxidation and oocyte apoptosis You Song BY-SA 1686: Deposition of Energy
343 Ecdysone receptor antagonism leading to mortality via mis-timed ecdysone receptor-responsive nuclear receptor cascade You Song BY-SA 2374: Increase, Ecdysone receptor antagonism
371 Photosystem II antagonism leading to growth inhibition via dysregulation of growth hormone You Song BY-SA None None
370 Photosystem II antagonism leading to growth inhibition via suppression of photosynthesis You Song BY-SA None None
369 Photosystem II antagonism leading to growth inhibition via oxidative damage You Song BY-SA None None
342 Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade You Song BY-SA 103: Increase, Ecdysone receptor hyperactivation
325 Reactive oxygen species leading to growth inhibition via oxidative DNA damage and cell death You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
326 Reactive oxygen species leading to growth inhibition via lipid peroxidation and decreased cell proliferation You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
327 Excessive reactive oxygen species production leading to mortality (1) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
328 Excessive reactive oxygen species production leading to mortality (2) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality