AOPs

OECD View API
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Showing 576 to 581 of 581 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
398 Decreased ALDH1A (RALDH) activity leading to decreased fertility via disrupted meiotic initiation of fetal oogonia Terje Svingen BY-SA 1880: Decreased, ALDH1A (RALDH) enzyme activity 406: decreased, Fertility Under Development 1.97
524 Gluten-driven immune activation leading to celiac disease in genetically predisposed individuals Antonio Fernandez Dumont BY-SA 2257: Celiac disease Under Review 1.98
437 Inhibition of mitochondrial electron transport chain (ETC) complexes leading to kidney toxicity Baki Sadi BY-SA 105: Inhibition, Mitochondrial Electron Transport Chain Complexes 814: Occurrence, Kidney toxicity Under Development 1.99
6 Antagonist binding to PPARĪ± leading to body-weight loss Kurt A. Gust BY-SA 998: Binding of antagonist, PPAR alpha 864: Decreased, Body Weight WPHA/WNT Endorsed 2.3
11 Percellome Toxicogenomics Approach for AOP Building: Case study on Pentachlorophenol Jun Kanno BY-SA 245: Activation, PXR/SXR None Under Development 2.5
136 Intracellular Acidification Induced Olfactory Epithelial Injury Leading to Site of Contact Nasal Tumors Undefined BY-SA 867: Decrease, Intracellular pH 872: Increase, Site of Contact Nasal Tumors Under Review 2.7