AOPs

OECD View API
Toggle for API info
The API endpoint defaults to 25 results per page, but you can adjust this by changing the per_page parameter in the URL.
Searches both title and fulltext content
Takes you to the requested AOP
Clear Search Terms Clears search terms and filters

Showing 76 to 100 of 581 AOPs

Clear Table Filters
ID Title Point of Contact License MIE AO OECD Status OECD Project
195 5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase Kellie Fay BY-SA 619: Inhibition, 5-hydroxytryptamine transporter (5-HTT; SERT) 1164: Increased, Population
196 Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation Jeanelle Martinez BY-SA 1215: TRPA1 activation, TRPA1 Receptor
197 Sodium channel (Nav1.1) inhibition leading to population decline Kellie Fay BY-SA 584: Inhibition, sodium channel None
199 ER mediated breast cancer AOP Molly M Morgan BY-SA None None
200 Estrogen receptor activation leading to breast cancer Molly M Morgan Open for adoption 111: Agonism, Estrogen receptor 1193: N/A, Breast Cancer
201 Juvenile hormone receptor agonism leading to male offspring induction associated population decline Knut Erik Tollefsen BY-SA 1205: Activation, Juvenile hormone receptor
203 5-hydroxytryptamine transporter inhibition leading to decreased reproductive success and population decline Kellie Fay BY-SA 619: Inhibition, 5-hydroxytryptamine transporter (5-HTT; SERT)
204 5-hydroxytryptamine transporter inhibition leading to increased reproductive success and population increase Kellie Fay BY-SA 619: Inhibition, 5-hydroxytryptamine transporter (5-HTT; SERT)
175 Thyroperoxidase inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 279: Thyroperoxidase, Inhibition 1101: Altered, Amphibian metamorphosis
164 Beta-2 adrenergic agonist activity leading to mesovarian leiomyomas in the rat and mouse Charles Wood BY-SA 1038: Activation, beta-2 adrenergic receptor 1044: Promotion, mesovarian leiomyomas
165 Antiestrogen activity leading to ovarian adenomas and granular cell tumors in the mouse Charles Wood BY-SA None
166 PPARalpha activation leading to pancreatic acinar tumors in the rat and mouse Charles Wood BY-SA None 1063: Increased, Pancreatic acinar tumors
167 Early-life estrogen receptor agonism leading to endometrial adenosquamous carcinoma via promotion of sine oculis homeobox 1 progenitor cells Travis Karschnik BY-SA 111: Agonism, Estrogen receptor 1070: Increased, adenosquamous carcinomas of endometrium
168 GnRH pulse disruption leading to mammary adenomas and carcinomas in the SD rat. Charles Wood BY-SA None 1079: Increased, Adenomas/carcinomas (mammary)
169 GnRH pulse disruption leading to pituitary adenomas and carcinomas in the SD rat. Charles Wood BY-SA None 1082: Increased, adenomas (pituitary)
170 Anti-dopaminergic activity leading to mammary adenomas and carcinomas in the SD rat Charles Wood BY-SA None 1079: Increased, Adenomas/carcinomas (mammary)
171 Chronic cytotoxicity of the serous membrane leading to pleural/peritoneal mesotheliomas in the rat. Charles Wood BY-SA None 1090: Increased, mesotheliomas
163 PPARgamma activation leading to sarcomas in rats, mice, and hamsters Charles Wood BY-SA 1028: Activation of specific nuclear receptors, PPAR-gamma activation None
176 Sodium Iodide Symporter (NIS) Inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 424: Inhibition, Na+/I- symporter (NIS) 1101: Altered, Amphibian metamorphosis
177 Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality Kellie Fay BY-SA 1103: Inhibition, Cyclooxygenase 1 activity
178 Nicotinic acetylcholine receptor activation contributes to mitochondrial dysfunction and leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
179 Varroa mite infestation increases virus levels leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
180 Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
181 Weather event contributes to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
182 Weather event contributes abnormal foraging leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony