AOPs

OECD View API
Toggle for API info
The API endpoint defaults to 25 results per page, but you can adjust this by changing the per_page parameter in the URL.
Searches both title and fulltext content
Takes you to the requested AOP
Clear Search Terms Clears search terms and filters

Showing 201 to 225 of 581 AOPs

Clear Table Filters
ID Title Point of Contact License MIE AO OECD Status OECD Project
327 Excessive reactive oxygen species production leading to mortality (1) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
328 Excessive reactive oxygen species production leading to mortality (2) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
329 Excessive reactive oxygen species production leading to mortality (3) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
330 Excessive reactive oxygen species production leading to mortality (4) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
331 Reactive oxygen species leading to growth inhibition via lipid peroxidation and cell death You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
332 Reactive oxygen species leading to growth inhibition via protein oxidation and decreased cell proliferation You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
333 Reactive oxygen species leading to growth inhibition via protein oxidation and cell death You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
334 Glucocorticoid Receptor Agonism Leading to Impaired Fin Regeneration Alexander Cole BY-SA 122: Increase, Glucocorticoid receptor activation 360: Decrease, Population growth rate
335 AOP for urothelial carcinogenesis due to chemical cytotoxicity by mitochondrial impairment Nathalia Pereira Souza BY-SA 177: Increase, Mitochondrial dysfunction 1763: Urothelial Tumor
338 DNA methyltransferase inhibition leading to population decline (3) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
342 Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade You Song BY-SA 103: Increase, Ecdysone receptor hyperactivation
384 Hyperactivation of ACE/Ang-II/AT1R axis leading to chronic kidney disease Young Jun Kim BY-SA 1853: Hyperactivation of ACE/Ang-II/AT1R axis 1603: Chronic kidney disease
404 Metabolic Syndrome leading to Toll Like Receptor dysregulation Gillina Bezemer BY-SA None None
403 combined unhealthy lifestyle factors leading to metabolic syndrome Gillina Bezemer BY-SA None None
402 Thyroid peroxidase (TPO) inhibition leads to periventricular heterotopia formation in the developing rat brain Katherine (Katie) O'Shaughnessy BY-SA 279: Thyroperoxidase, Inhibition
401 G protein-coupled estrogen receptor 1 (GPER) signal pathway in the lipid metabolism disrupting effects Fei Li BY-SA 2029: protein-coupled estrogen receptor 1 (GPER) activation 1489: Increase, Steatohepatitis
400 Inhibition of CYP26B1 activity in fetal testis leading to reduced fertility Terje Svingen BY-SA 1887: Inhibition of CYP26B1 activity 406: decreased, Fertility
399 Inhibition of Fyna leading to increased mortality via decreased eye size (Microphthalmos) Vid Modic BY-SA 1884: Inhibition of Fyna
396 Deposition of ionizing energy leads to population decline via impaired meiosis Erica Maremonti BY-SA 1550: Deposition of Ionizing Energy
393 AOP for thyroid disorder caused by triphenyl phosphate via TRĪ² activation Fei Li BY-SA 1158: Increased, Hepatic thyroid hormone uptake/transport None
389 Oxygen-evolving complex damage leading to population decline via inhibition of photosynthesis Knut Erik Tollefsen BY-SA 1865: Increase, Oxygen-evolving complex damage
388 Deposition of ionising energy leading to population decline via programmed cell death Knut Erik Tollefsen BY-SA 1686: Deposition of Energy
387 Deposition of ionising energy leading to population decline via mitochondrial dysfunction Knut Erik Tollefsen BY-SA 1686: Deposition of Energy
386 Deposition of ionizing energy leading to population decline via inhibition of photosynthesis Knut Erik Tollefsen BY-SA 1686: Deposition of Energy
385 Viral spike protein interaction with ACE2 leads to microvascular dysfunction, via ACE2 dysregulation Julija Filipovska BY-SA 1739: Binding to ACE2 None