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AOP Fulltext Search Results

ID Title Point of Contact License MIE AO OECD Status OECD Project
21 Aryl hydrocarbon receptor activation leading to early life stage mortality, via increased COX-2 Markus Hecker BY-SA
  • Activation, AhR
WPHA/WNT Endorsed 1.27
150 Aryl hydrocarbon receptor activation leading to early life stage mortality, via reduced VEGF Amani Farhat BY-SA
  • Activation, AhR
  • Increase, Early Life Stage Mortality
WPHA/WNT Endorsed 1.7
277 Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response Takao Ashikaga BY-SA
  • Impaired IL-1R1 signaling in T cell
  • Impairment, T-cell dependent antibody response
WPHA/WNT Endorsed 1.48
483 Deposition of Energy Leading to Learning and Memory Impairment Vinita Chauhan All rights reserved
  • Deposition of Energy
  • Impairment, Learning and memory
439 Activation of the AhR leading to metastatic breast cancer Louise Benoit BY-SA
  • Activation, AhR
  • metastatic breast cancer
Under Development 1.105
293 Increased DNA damage leading to increased risk of breast cancer Jessica Helm BY-SA
  • Increase, DNA damage
  • Increase, Mutations
  • Increased, Ductal Hyperplasia
  • N/A, Breast Cancer
Under Development 1.80
294 Increased reactive oxygen and nitrogen species (RONS) leading to increased risk of breast cancer Jessica Helm BY-SA
  • Increase in reactive oxygen and nitrogen species (RONS)
  • Increase, DNA damage
  • Increase, Mutations
  • Increased, Ductal Hyperplasia
  • N/A, Breast Cancer
Under Development 1.80
3 Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits Andrea Terron BY-SA
  • Binding of inhibitor, NADH-ubiquinone oxidoreductase (complex I)
  • Parkinsonian motor deficits
WPHA/WNT Endorsed 1.33
43 Disruption of VEGFR Signaling Leading to Developmental Defects Tom Knudsen BY-SA
  • Inhibition, VegfR2
  • Increased, Developmental Defects
WPHA/WNT Endorsed 1.6
149 Peptide Oxidation Leading to Hypertension Frazer Lowe BY-SA
  • Peptide Oxidation
  • Hypertension
Under Development 1.50