| 2390 |
KE5: Altered circulating reproductive hormones
Short Name
reproductive hormonal Imbalance
|
0 |
Organ |
Nov 7, 2025 |
Nov 7, 2025 |
616: organic UV filter and its Photoproducts reproductive toxicity pathways
|
| 2391 |
Reduced fertility / fecundity
Short Name
Reduced fertility
|
0 |
Individual |
Nov 7, 2025 |
Nov 7, 2025 |
616: organic UV filter and its Photoproducts reproductive toxicity pathways
|
| 2327 |
Decrease, Cell growth
Short Name
Decrease, Cell growth
|
0 |
Cellular |
May 23, 2025 |
May 23, 2025 |
600: Excessive reactive oxygen species leading to growth inhibition via fatty acid oxidation and reduced cell growth
|
| 2341 |
Tricarboxylic acid (TCA) cycle, disrupted
Short Name
TCA cycle, disrupted
|
0 |
Molecular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2340 |
Oligomerisation of dihydrolipoamide acetyltransferase (DLAT), increased
Short Name
Oligomerisation of DLAT, increased
|
0 |
Molecular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2339 |
Intracellular copper, increased
Short Name
Intracellular copper, increased
|
0 |
Cellular |
Aug 13, 2025 |
Oct 16, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2337 |
Increase, perilipin-2
Short Name
Increase, PLIN2
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2336 |
Increase, SREBF1
Short Name
Increase, SREBF1
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2335 |
Increase, body mass index
Short Name
Increase, BMI
|
0 |
Individual |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2334 |
Increase, DGAT1
Short Name
Increase, DGAT1
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2333 |
Increase, Fat mass
Short Name
Increase, Fat mass
|
0 |
Organ |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2332 |
Increase, Lipid droplet
Short Name
Increase, Lipid droplet
|
0 |
Cellular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2331 |
Activation, Mineralocorticoid Receptor
Short Name
Activation, MR
|
0 |
Molecular |
Jul 25, 2025 |
Jul 25, 2025 |
580: Mineralocorticoid Receptor Activation Leading to Increased Body Mass Index
|
| 2342 |
Iron-sulfur cluster assembly, impaired
Short Name
Fe-S cluster assembly, impaired
|
0 |
Molecular |
Aug 13, 2025 |
Oct 30, 2025 |
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
|
| 2326 |
CTL cytotoxic activity disruption
Short Name
CTL cytotoxicity
|
0 |
Cellular |
May 22, 2025 |
Feb 24, 2026 |
578: AhR activation leading to cancer progression via immunosuppression
|
| 2325 |
Decreased number of LT CD8+ cells
Short Name
Decreased number of LT CD8+ cells
|
0 |
Cellular |
May 16, 2025 |
Jun 11, 2025 |
None
|
| 2324 |
Increased of Treg/Th17 cell ratio
Short Name
Dysregulation of Treg/Th17 cell ratio
|
0 |
Cellular |
May 16, 2025 |
Feb 24, 2026 |
578: AhR activation leading to cancer progression via immunosuppression
|
| 2323 |
Over-expression of PD-L1 in cancer cells
Short Name
Over-expression of PD-L1 in cancer cells
|
0 |
Molecular |
May 15, 2025 |
Sep 30, 2025 |
578: AhR activation leading to cancer progression via immunosuppression
|
| 2321 |
Decreased, CYP11A1 activity
Short Name
Decreased, CYP11A1 activity
|
0 |
Molecular |
Apr 8, 2025 |
Apr 8, 2025 |
None
|
| 2320 |
Decreased, 17-beta-HSD3 activity
Short Name
Decreased, 17βHSD3 activity
|
0 |
Molecular |
Apr 8, 2025 |
Apr 8, 2025 |
None
|
| 2319 |
Decreased, Pregnenolone levels
Short Name
Decreased, Pregnenolone levels
|
0 |
Tissue |
Apr 8, 2025 |
Apr 8, 2025 |
None
|
| 2318 |
Decreased 3-beta-HSD activity
Short Name
Decreased 3βHSD activity
|
0 |
Tissue |
Apr 8, 2025 |
Apr 8, 2025 |
None
|
| 2314 |
Increased, Cardiovascular dysfunction
Short Name
Cardiovascular dysfunction
|
0 |
Individual |
Mar 11, 2025 |
Mar 11, 2025 |
None
|
| 2352 |
Increased, MMP
Short Name
Increased, MMP
|
0 |
Cellular |
Aug 16, 2025 |
Aug 16, 2025 |
592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
|
| 2361 |
Hypothalamus–Pituitary–Gonad) axis disruption
Short Name
HPG axis disruption
|
0 |
Organ |
Sep 2, 2025 |
Sep 2, 2025 |
None
|