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Showing 76 to 100 of 1937 Key Events

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ID Title Event Component Count Biological Organization Created At Last Updated AOPs
2369 Granulosa cell damage
0 Cellular Sep 9, 2025 Sep 9, 2025 595: Emerging OPFRS reproductive outcome pathway
2368 immature oocyte
0 Cellular Sep 9, 2025 Sep 9, 2025 None
2367 Steroidogenesis Dysregulation
0 Cellular Sep 9, 2025 Sep 9, 2025 595: Emerging OPFRS reproductive outcome pathway
2366 ovarian retardation
0 Organ Sep 9, 2025 Sep 9, 2025 595: Emerging OPFRS reproductive outcome pathway
2365 Anogenital distance (AGD), increased
0 Tissue Sep 5, 2025 Dec 8, 2025 547: Androgen receptor agonism leading to long anogenital distance in female offspring
2363 Elevated mitochondrial ROS and dysfunction
1 Cellular Sep 5, 2025 Oct 3, 2025
2362 Redox cycling of a chemical by mitochondria
0 Molecular Sep 5, 2025 Oct 3, 2025 593: Redox cycling of a chemical by mitochondria leads to degeneration of nigrostriatal dopaminergic neurons
2361 Hypothalamus–Pituitary–Gonad) axis disruption
0 Organ Sep 2, 2025 Sep 2, 2025 None
2360 Activation of steroidogenesis
0 Cellular Sep 2, 2025 Sep 2, 2025 None
2359 HPG axis
0 Molecular Aug 29, 2025 Aug 29, 2025 None
2358 endocrine disruption
0 Molecular Aug 29, 2025 Aug 29, 2025 None
2357 ovary
0 Molecular Aug 29, 2025 Aug 29, 2025 None
2356 vitellogenin
0 Molecular Aug 29, 2025 Aug 29, 2025 None
2355 Disrupted, Spermatogenesis and Sperm quality
0 Organ Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2354 Activation, Apoptosis signaling
0 Cellular Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2353 Disrupted, energy metabolism
0 Cellular Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2352 Increased, MMP
0 Cellular Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2351 Increased, OXPHOS
0 Cellular Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2350 Decreased, Glycolysis
0 Cellular Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2349 Inhibition of LDH activity
0 Molecular Aug 16, 2025 Aug 16, 2025 592: DBDPE-induced DNA strand breaks and LDH activity inhibition leading to population growth rate decline via energy metabolism disrupt and apoptosis
2348 Inhibition, Liver regeneration
0 Organ Aug 16, 2025 Aug 16, 2025 591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
2347 Increase, Lipid degradation
0 Cellular Aug 16, 2025 Aug 16, 2025 591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
2346 Decrease, Proliferating Cell Nuclear Antigen
0 Molecular Aug 16, 2025 Aug 16, 2025 591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
2345 Activation, MAPK
0 Molecular Aug 16, 2025 Aug 16, 2025 591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration
2344 Upregulation, growth arrest and DNA-damage-inducible beta a
0 Molecular Aug 16, 2025 Aug 16, 2025 591: DBDPE-induced DNA damage increase in liver leading to Non-alcoholic fatty liver disease via liver steatosis and inhibition of regeneration