API

Relationship: 688

Title

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Reduced, Reproductive Success leads to Declining, Population trajectory

Upstream event

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Reduced, Reproductive Success

Downstream event

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Declining, Population trajectory

Key Event Relationship Overview

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AOPs Referencing Relationship

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AOP Name Directness Weight of Evidence Quantitative Understanding
Cyclooxygenase inhibition leading to reproductive dysfunction directly leads to Strong Strong
Cyclooxygenase inhibition leading to reproductive dysfunction via interference with spindle assembly checkpoint directly leads to Strong Strong

Taxonomic Applicability

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Sex Applicability

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Life Stage Applicability

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How Does This Key Event Relationship Work

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Weight of Evidence

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Biological Plausibility

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Empirical Support for Linkage

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Uncertainties or Inconsistencies

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Quantitative Understanding of the Linkage

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Evidence Supporting Taxonomic Applicability

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References

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