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Showing 301 to 325 of 3158 KERs

ID	Upstream Event	Downstream Event	Creation Date	Last Updated	AOPs

573	572: Decrease, Number of worker bees	568: impaired, Hive thermoregulation	Nov 29, 2016	Dec 3, 2016	2 AOPs 84: Suppression of immune system contributes to impaired development and leads to colony loss/failure 80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure
574	568: impaired, Hive thermoregulation	563: Death/Failure, Colony	Nov 29, 2016	Dec 3, 2016	2 AOPs 84: Suppression of immune system contributes to impaired development and leads to colony loss/failure 80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure
575	576: Increased, Viral susceptibility	560: Abnormal, Foraging activity and behavior	Nov 29, 2016	Dec 3, 2016	1 AOP 85: Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure
576	578: Decreased, Glucose oxidase enzyme activity	579: Decreased, Hydrogen peroxide production	Nov 29, 2016	Dec 3, 2016	1 AOP 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
577	579: Decreased, Hydrogen peroxide production	580: Reduced, Antiseptic incorporated in food	Nov 29, 2016	Dec 3, 2016	1 AOP 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
578	580: Reduced, Antiseptic incorporated in food	564: Abnormal, Roll change within caste	Nov 29, 2016	Dec 3, 2016	1 AOP 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
579	564: Abnormal, Roll change within caste	561: Reduced, Food storage	Nov 29, 2016	Dec 3, 2016	1 AOP 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
580	564: Abnormal, Roll change within caste	572: Decrease, Number of worker bees	Nov 29, 2016	Dec 3, 2016	None
581	559: Activation, Nicotinic acetylcholine receptor	177: Increase, Mitochondrial dysfunction	Nov 29, 2016	Dec 3, 2016	5 AOPs 87: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure 77: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure 79: Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure 78: Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1
582	177: Increase, Mitochondrial dysfunction	386: Neuronal network function, Decreased	Nov 29, 2016	Dec 3, 2016	1 AOP 78: Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1
583	341: Impairment, Learning and memory	560: Abnormal, Foraging activity and behavior	Nov 29, 2016	Dec 3, 2016	4 AOPs 87: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure 77: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 89: Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure 88: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste
584	560: Abnormal, Foraging activity and behavior	561: Reduced, Food storage	Nov 29, 2016	Dec 3, 2016	None
585	584: Inhibition, sodium channel	585: Decreased, Sodium conductance 1	Nov 29, 2016	Dec 3, 2016	3 AOPs 91: Sodium channel inhibition leading to reduced survival 93: sodium channel inhibition leading to increased predation 94: Sodium channel inhibition leading to congenital malformations
586	585: Decreased, Sodium conductance 1	586: Reduced, swimming speed	Nov 29, 2016	Dec 3, 2016	3 AOPs 91: Sodium channel inhibition leading to reduced survival 93: sodium channel inhibition leading to increased predation 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
587	586: Reduced, swimming speed	587: Reduced, feeding 1	Nov 29, 2016	Dec 3, 2016	2 AOPs 91: Sodium channel inhibition leading to reduced survival 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
588	586: Reduced, swimming speed	588: Increased, predation	Nov 29, 2016	Dec 3, 2016	3 AOPs 91: Sodium channel inhibition leading to reduced survival 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival 93: sodium channel inhibition leading to increased predation
589	587: Reduced, feeding 1	588: Increased, predation	Nov 29, 2016	Dec 3, 2016	2 AOPs 91: Sodium channel inhibition leading to reduced survival 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
590	584: Inhibition, sodium channel	444: Increased, Atrioventricular block and bradycardia	Nov 29, 2016	Dec 3, 2016	None
591	444: Increased, Atrioventricular block and bradycardia	445: Respiratory distress/arrest	Nov 29, 2016	Dec 3, 2016	1 AOP 94: Sodium channel inhibition leading to congenital malformations
592	445: Respiratory distress/arrest	590: N/A, hypoxia	Nov 29, 2016	Dec 3, 2016	1 AOP 94: Sodium channel inhibition leading to congenital malformations
593	590: N/A, hypoxia	591: Increased, amputations	Nov 29, 2016	Dec 3, 2016	1 AOP 94: Sodium channel inhibition leading to congenital malformations
594	585: Decreased, Sodium conductance 1	444: Increased, Atrioventricular block and bradycardia	Nov 29, 2016	Dec 3, 2016	1 AOP 94: Sodium channel inhibition leading to congenital malformations
595	588: Increased, predation	592: Reduced, survival	Nov 29, 2016	Dec 3, 2016	2 AOPs 91: Sodium channel inhibition leading to reduced survival 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
596	587: Reduced, feeding 1	592: Reduced, survival	Nov 29, 2016	Dec 3, 2016	1 AOP 91: Sodium channel inhibition leading to reduced survival
597	593: Inhibition, Ether-a-go-go (ERG) voltage-gated potassium channel	585: Decreased, Sodium conductance 1	Nov 29, 2016	Dec 3, 2016	1 AOP 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival

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