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Showing 76 to 100 of 3130 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
3401 1924: Increased,Cardiac fibrosis 1929: Increased incidence of cardiovascular morbidity and mortality Nov 20, 2024 Nov 20, 2024 None
2948 1365: Increase, Apoptosis 1430: Inhibition of neurotransmitter release Jun 20, 2023 Jun 20, 2023 None
2852 1963: Torsades de Pointes 351: Increased Mortality Jan 29, 2023 Jan 29, 2023 None
2853 1962: Prolongation of QT interval 1106: Occurrence, cardiac arrhythmia Jan 29, 2023 Jan 29, 2023 None
2854 1106: Occurrence, cardiac arrhythmia 1919: Increased,Cardiac dysfunction Jan 29, 2023 Jan 29, 2023 None
2855 1919: Increased,Cardiac dysfunction 351: Increased Mortality Jan 29, 2023 Jan 29, 2023 None
2856 1635: Increase, DNA strand breaks 2066: Altered Signaling Mar 10, 2023 Mar 21, 2023 None
2863 1825: Increase, Cell death 758: Hippocampal Physiology, Altered Apr 3, 2023 Apr 3, 2023 None
2840 2066: Altered Signaling 2098: Abnormal Neural Remodeling Jan 25, 2023 Mar 21, 2023 None
2843 2066: Altered Signaling 2089: Altered Bone Cell Homeostasis Jan 25, 2023 Mar 22, 2023 None
2874 2124: increased, Bax 1825: Increase, Cell death Apr 4, 2023 Apr 4, 2023 None
2884 295: Induction, Upregulation of glucuronyltransferase activity 2133: Increase, Glucuronidation of T4 Apr 12, 2023 Apr 12, 2023 None
2885 2133: Increase, Glucuronidation of T4 961: Increased, Clearance of thyroxine from serum Apr 12, 2023 Apr 12, 2023 None
2888 18: Activation, AhR 345: N/A, Liver Steatosis Apr 13, 2023 Apr 13, 2023 None
2889 345: N/A, Liver Steatosis 55: Cell injury/death Apr 13, 2023 Apr 13, 2023 None
2890 55: Cell injury/death 1494: Leukocyte recruitment/activation Apr 13, 2023 Apr 13, 2023 None
2891 1494: Leukocyte recruitment/activation 1501: Increase, ECM deposition Apr 13, 2023 Apr 13, 2023 None
2873 2123: decreased, Bcl-2 1825: Increase, Cell death Apr 4, 2023 Apr 4, 2023 None
2926 25: Agonism, Androgen receptor 2139: Reduction, the ratio of E2/11-KT in plasma May 22, 2023 May 22, 2023 None
2927 1702: Suppression of T cell activation 1700: Impaired IL-1R1 signaling May 24, 2023 May 24, 2023 None
2931 179: Decrease, Fatty acid β-oxidation 1816: Mitochondrial dysfunction EMPTY May 25, 2023 May 25, 2023 None
2932 1816: Mitochondrial dysfunction EMPTY 2144: Impaired insulin signaling May 25, 2023 May 25, 2023 None
2576 1196: Increased, Invasion 1193: N/A, Breast Cancer Feb 15, 2022 Feb 15, 2022 None
2578 1376: Increase, angiogenesis 1193: N/A, Breast Cancer Feb 15, 2022 Feb 15, 2022 None
2579 1971: tumor growth 1193: N/A, Breast Cancer Feb 15, 2022 Feb 15, 2022 None