Key Event Relationships (KERs)

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Showing 201 to 225 of 3131 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
428 351: Increased Mortality 442: Decreased, Population trajectory Nov 29, 2016 Dec 20, 2019 None
411 228: demethylation, PPARg promoter 54: Up Regulation, CD36 Nov 29, 2016 Nov 29, 2016
405 348: Malformation, Male reproductive tract 406: decreased, Fertility Nov 29, 2016 Dec 2, 2016
683 669: Reduction, Neuronal synaptic inhibition 682: Generation, Amplified excitatory postsynaptic potential (EPSP) Nov 29, 2016 May 15, 2018
684 682: Generation, Amplified excitatory postsynaptic potential (EPSP) 616: Occurrence, A paroxysmal depolarizing shift Nov 29, 2016 May 15, 2018
685 685: Reduced, Prostaglandins, ovary 488: Decrease, Ovulation Nov 29, 2016 Dec 3, 2016
686 79: Inhibition, Cyclooxygenase activity 685: Reduced, Prostaglandins, ovary Nov 29, 2016 Dec 3, 2016
687 488: Decrease, Ovulation 675: Reduced, Reproductive Success Nov 29, 2016 Dec 3, 2016
689 79: Inhibition, Cyclooxygenase activity 687: Reduced, Prostaglandin E2 concentration, hypothalamus Nov 29, 2016 Dec 3, 2016
690 687: Reduced, Prostaglandin E2 concentration, hypothalamus 689: Reduced, Gonadotropin releasing hormone, hypothalamus Nov 29, 2016 Dec 3, 2016
691 689: Reduced, Gonadotropin releasing hormone, hypothalamus 690: Reduced, Luteinizing hormone (LH), plasma Nov 29, 2016 Dec 3, 2016
692 690: Reduced, Luteinizing hormone (LH), plasma 691: Reduced, Maturation inducing steroid, plasma Nov 29, 2016 Dec 3, 2016
693 691: Reduced, Maturation inducing steroid, plasma 692: Reduced, Maturation inducing steroid receptor signalling, oocyte Nov 29, 2016 Dec 3, 2016
694 692: Reduced, Maturation inducing steroid receptor signalling, oocyte 693: Increased, cyclic adenosine monophosphate Nov 29, 2016 Dec 3, 2016
695 693: Increased, cyclic adenosine monophosphate 675: Reduced, Reproductive Success Nov 29, 2016 Dec 3, 2016 None
696 693: Increased, cyclic adenosine monophosphate 694: Reduced, Meiotic prophase I/metaphase I transition, oocyte Nov 29, 2016 Dec 3, 2016
697 694: Reduced, Meiotic prophase I/metaphase I transition, oocyte 675: Reduced, Reproductive Success Nov 29, 2016 Dec 3, 2016
698 692: Reduced, Maturation inducing steroid receptor signalling, oocyte 695: Upregulated, Spindle assembly checkpoint protein Mad2-oocyte Nov 29, 2016 Dec 3, 2016
699 695: Upregulated, Spindle assembly checkpoint protein Mad2-oocyte 696: Increased, Chromosome misseggregation Nov 29, 2016 Dec 3, 2016
700 696: Increased, Chromosome misseggregation 675: Reduced, Reproductive Success Nov 29, 2016 Dec 3, 2016
701 697: impaired, ion channels 698: Altered, Action Potential Nov 29, 2016 Dec 3, 2016
702 698: Altered, Action Potential 699: Increased, cardiac arrthymia Nov 29, 2016 Dec 3, 2016
703 699: Increased, cardiac arrthymia 351: Increased Mortality Nov 29, 2016 Dec 3, 2016
452 12: AchE Inhibition 351: Increased Mortality Nov 29, 2016 Dec 20, 2019
453 12: AchE Inhibition 442: Decreased, Population trajectory Nov 29, 2016 Dec 20, 2019 None