Key Event Relationships (KERs)

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Showing 3101 to 3125 of 3158 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
1315 962: Increase, Mucin production 1251: Chronic, Mucus hypersecretion Nov 29, 2016 Aug 30, 2021 None
1324 1255: induced spawning 1141: Decreased, Reproductive Success Jan 13, 2017 Jan 13, 2017 None
1329 1162: Increased, cilia movement 1255: induced spawning Jan 17, 2017 Jan 17, 2017 None
1330 1252: Binding, topoisomerase II 1253: MLL translocation Jan 20, 2017 Apr 26, 2017 None
1348 1267: Decrease, Ecdysis motor program activity 1268: Decrease, Excitatory postsynaptic potential Feb 9, 2017 Feb 9, 2017 None
1349 1268: Decrease, Excitatory postsynaptic potential 993: Decrease, Abdominal muscle contraction Feb 9, 2017 Feb 9, 2017 None
1352 317: Altered, Cardiovascular development/function 350: Increase, Mortality Feb 9, 2017 Feb 9, 2017 None
1354 1271: Activation of TGF-β signaling 1272: Increase, Myofibroblast expansion Feb 15, 2017 Feb 15, 2017 None
1355 1271: Activation of TGF-β signaling 1273: Expression of Collagen Feb 15, 2017 Feb 15, 2017 None
1356 1272: Increase, Myofibroblast expansion 1274: Production of α-smooth muscle actin Feb 15, 2017 Feb 15, 2017 None
1357 1273: Expression of Collagen 1275: Collagen Deposition Feb 15, 2017 Feb 15, 2017 None
1358 1274: Production of α-smooth muscle actin 1276: Lung fibrosis Feb 15, 2017 Feb 15, 2017 None
1390 1296: Increase, insulin 1297: Activation, insulin receptor Apr 12, 2017 Apr 12, 2017 None
1391 1297: Activation, insulin receptor 1298: Activation, mTORC2 Apr 12, 2017 Apr 12, 2017 None
1392 1298: Activation, mTORC2 1299: Activation, AKT Apr 12, 2017 Apr 12, 2017 None
1393 1298: Activation, mTORC2 1300: Activation, mTORC1 Apr 12, 2017 Apr 12, 2017 None
1394 1299: Activation, AKT 1301: Activation, SREBP-1 Apr 12, 2017 Apr 12, 2017 None
1395 1300: Activation, mTORC1 1302: Activation, L-FABP Apr 12, 2017 Apr 12, 2017 None
1396 1300: Activation, mTORC1 1303: Activation, HSD17B4 Apr 12, 2017 Apr 12, 2017 None
1397 1301: Activation, SREBP-1 1304: Activation, FXR Apr 12, 2017 Apr 12, 2017 None
1398 1299: Activation, AKT 1300: Activation, mTORC1 Apr 12, 2017 Apr 12, 2017 None
1399 1300: Activation, mTORC1 1301: Activation, SREBP-1 Apr 12, 2017 Apr 12, 2017 None
1400 1299: Activation, AKT 1302: Activation, L-FABP Apr 12, 2017 Apr 12, 2017 None
1401 1302: Activation, L-FABP 1305: Increase, cytosolic fatty acid Apr 12, 2017 Apr 12, 2017 None
1402 228: demethylation, PPARg promoter 1301: Activation, SREBP-1 Apr 12, 2017 Apr 12, 2017 None