Key Event Relationships (KERs)

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Showing 3126 to 3150 of 3158 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
1403 1301: Activation, SREBP-1 258: Activation, SCD-1 Apr 12, 2017 Apr 12, 2017 None
1404 258: Activation, SCD-1 1306: Increase, De novo lipogenesis Apr 12, 2017 Apr 12, 2017 None
1405 1306: Increase, De novo lipogenesis 1305: Increase, cytosolic fatty acid Apr 12, 2017 Apr 12, 2017 None
1406 478: Activation, NRF2 1304: Activation, FXR Apr 12, 2017 Apr 12, 2017 None
1407 1304: Activation, FXR 480: Activation, SHP Apr 12, 2017 Apr 12, 2017 None
1408 1304: Activation, FXR 227: Activation, PPARα Apr 12, 2017 Apr 12, 2017 None
1409 480: Activation, SHP 227: Activation, PPARα Apr 12, 2017 Apr 12, 2017 None
1410 227: Activation, PPARα 1303: Activation, HSD17B4 Apr 12, 2017 Apr 12, 2017 None
1411 1303: Activation, HSD17B4 451: Inhibition, Mitochondrial fatty acid beta-oxidation Apr 12, 2017 Apr 12, 2017 None
1412 480: Activation, SHP 1307: Inhibition, LXR Apr 12, 2017 Apr 12, 2017 None
1413 1307: Inhibition, LXR 468: Inhibition, PPAR alpha Apr 12, 2017 Apr 12, 2017 None
1414 480: Activation, SHP 1308: Inhibition, LRH-1 Apr 12, 2017 Apr 12, 2017 None
1415 1303: Activation, HSD17B4 1312: Increase, Fatty acid β-oxidation Apr 13, 2017 Apr 13, 2017 None
1417 1312: Increase, Fatty acid β-oxidation 1313: Decrease, cytosolic fatty acid Apr 13, 2017 Apr 13, 2017 None
1418 1310: Activation, PI3K 1299: Activation, AKT Apr 13, 2017 Apr 13, 2017 None
1419 1310: Activation, PI3K 1302: Activation, L-FABP Apr 13, 2017 Apr 13, 2017 None
1420 1310: Activation, PI3K 1309: Activation, aPKC Apr 13, 2017 Apr 13, 2017 None
1421 1309: Activation, aPKC 1301: Activation, SREBP-1 Apr 13, 2017 Apr 13, 2017 None
1422 116: Activation, FAS 1306: Increase, De novo lipogenesis Apr 13, 2017 Apr 13, 2017 None
1423 1302: Activation, L-FABP 228: demethylation, PPARg promoter Apr 13, 2017 Apr 13, 2017 None
1424 228: demethylation, PPARg promoter 116: Activation, FAS Apr 13, 2017 Apr 13, 2017 None
1425 1314: Activation, LRH-1 116: Activation, FAS Apr 13, 2017 Apr 13, 2017 None
1467 209: Peptide Oxidation 1194: Increase, DNA Damage Apr 15, 2017 Apr 15, 2017 None
1469 1365: Increase, Apoptosis 1366: Decrease, Oogenesis Apr 15, 2017 Apr 15, 2017 None
1470 1366: Decrease, Oogenesis 488: Decrease, Ovulation Apr 15, 2017 Apr 15, 2017 None