| 3800 |
1879: Bulky DNA adducts, increase |
1635: Increase, DNA strand breaks |
Jun 29, 2026 |
Jun 29, 2026 |
1 AOP
|
| 3799 |
1879: Bulky DNA adducts, increase |
1636: Increase, Chromosomal aberrations |
Jun 29, 2026 |
Jun 29, 2026 |
1 AOP
|
| 3798 |
245: Activation, PXR/SXR |
2429: Instability of INSIG1 |
Jun 9, 2026 |
Jun 9, 2026 |
None
|
| 3797 |
1635: Increase, DNA strand breaks |
55: Cell injury/death |
May 12, 2026 |
Jun 23, 2026 |
1 AOP
|
| 3796 |
2423: Hepatic SHP, decreased |
1421: Activated, LXR |
Apr 28, 2026 |
Apr 28, 2026 |
1 AOP
|
| 3795 |
2421: FXR inhibition |
2423: Hepatic SHP, decreased |
Apr 28, 2026 |
Apr 28, 2026 |
1 AOP
|
| 3794 |
1417: NFE2/Nrf2 repression |
2421: FXR inhibition |
Apr 28, 2026 |
Apr 28, 2026 |
1 AOP
|
| 3793 |
902: Inflammation, Liver |
1489: Increase, Steatohepatitis |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3792 |
902: Inflammation, Liver |
1931: Disruption of the intestinal barrier |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3791 |
1392: Increase, Oxidative Stress |
902: Inflammation, Liver |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3790 |
2428: PAMPs, increased |
1392: Increase, Oxidative Stress |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3789 |
1931: Disruption of the intestinal barrier |
2428: PAMPs, increased |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3788 |
2427: Bile acid composition, altered |
1931: Disruption of the intestinal barrier |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3787 |
2426: BSEP (ABCB11), decreased |
2427: Bile acid composition, altered |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3786 |
2425: Intrahepatic bile acids, increased |
2426: BSEP (ABCB11), decreased |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3785 |
2424: Hepatic CYP7A1, increased |
2425: Intrahepatic bile acids, increased |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3784 |
2422: Decreased FGF15/FGF19 |
2424: Hepatic CYP7A1, increased |
Apr 27, 2026 |
Apr 27, 2026 |
1 AOP
|
| 3783 |
1757: Decrease, Sperm count |
406: decreased, Fertility |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3782 |
1890: Germ cell loss, male |
1757: Decrease, Sperm count |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3781 |
1889: premature meiosis, male germ cells |
1890: Germ cell loss, male |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3780 |
2420: Increased, RAR activation |
1889: premature meiosis, male germ cells |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3779 |
1888: increased atRA concentration |
2420: Increased, RAR activation |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3778 |
1887: CYP26B1, inhibition |
1888: increased atRA concentration |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3777 |
2419: Decreased, RAR activation |
1882: Disrupted, meiotic initiation in oocyte |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|
| 3776 |
1881: Decreased, atRA concentration |
2419: Decreased, RAR activation |
Apr 24, 2026 |
Apr 24, 2026 |
1 AOP
|