Prototypical Stressors

Showing 651 to 675 of 874 Prototypical Stressors

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ID Prototypical Stressor Name Associated Chemical(s): Name, CAS-RN, DTXSID Associated AOPs
788 Halogenated Hydrocarbons
519: Cardiac ion channels blockade leading to increased incidence of cardiovascular morbidity and mortality
789 terfenadine
519: Cardiac ion channels blockade leading to increased incidence of cardiovascular morbidity and mortality
790 Flecainide
553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
791 Bupivacaine
553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
792 Tetracaine
553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
793 Saxitoxin
553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
794 Tetrodotoxin derivatives
553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
796 Epinephrine
554: β-adrenergic receptor agonists leading to arrhythmias.
797 Norepinephrine
554: β-adrenergic receptor agonists leading to arrhythmias.
798 Theophylline
554: β-adrenergic receptor agonists leading to arrhythmias.
800 Sotalol
555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure
801 Dofetilide
555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure
802 ziprasidone
555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure
804 Digoxin
556: Decreased Na/K ATPase activity leading to heart failure
805 Ouabain
556: Decreased Na/K ATPase activity leading to heart failure
806 Thapsigargin
556: Decreased Na/K ATPase activity leading to heart failure
807 Enoximone
558: Phosphodiesterase inhibition leading to heart failure
808 Roflumilast
558: Phosphodiesterase inhibition leading to heart failure
809 Catecholamines
558: Phosphodiesterase inhibition leading to heart failure
810 Forskolin
558: Phosphodiesterase inhibition leading to heart failure
813 Donepezil
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
814 Neostigmine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
815 Pyridostigmine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
816 Diazinon
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
817 Sarin
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias