Prototypical Stressors

Showing 676 to 700 of 874 Prototypical Stressors

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ID Prototypical Stressor Name Associated Chemical(s): Name, CAS-RN, DTXSID Associated AOPs
818 Tabun
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
819 Carbaryl
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
820 Aldicarb
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
821 Physostigmine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
822 Carbofuran
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
823 Pilocarpine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
824 Bethanechol
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
825 Isobutylmethylxanthine
  • Isobutylmethylxanthine, CAS-RN: 28822-58-4, DTXSID0040549
561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
826 Aldrin
  • Aldrin, CAS-RN: 309-00-2, DTXSID8020040
561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
827 Technical chlordane
  • Technical chlordane, CAS-RN: 12789-03-6, DTXSID5023954
561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
828 Methoxychlor
  • Methoxychlor, CAS-RN: 72-43-5, DTXSID9020827
561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
829 Oxadiazon
  • Oxadiazon, CAS-RN: 19666-30-9, DTXSID3024239
561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
830 Metolachlor
  • Metolachlor, CAS-RN: 51218-45-2, DTXSID4022448
561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
831 Cilobradine
562: HCN Channel Inhibition leading to Arrhythmias
832 4-bromo-2-(methylamino)-benzimidazole
562: HCN Channel Inhibition leading to Arrhythmias
833 N-Methyl-D-aspartic acid
  • N-Methyl-D-aspartic acid, CAS-RN: 6384-92-5, DTXSID8041082
475: Binding of chemicals to ionotropic glutamate receptors leads to impairment of learning and memory via loss of drebrin from dendritic spines of neurons
835 3,3',5,5'-Tetrabromobisphenol A
  • 3,3',5,5'-Tetrabromobisphenol A, CAS-RN: 79-94-7, DTXSID1026081
565: 17β-Hydroxysteroid dehydrogenase 2, inhibition leading to activation, estrogen receptor alpha
836 7,12-Dimethylbenz(a)anthracene
  • 7,12-Dimethylbenz(a)anthracene, CAS-RN: 57-97-6, DTXSID1020510
563: Aryl hydrocarbon Receptor (AHR) activation causes Premature Ovarian Insufficiency via Bax mediated apoptosis
837 Gluten
524: Gluten-driven immune activation leading to celiac disease in genetically predisposed individuals
838 Bacterial or viral Infections
524: Gluten-driven immune activation leading to celiac disease in genetically predisposed individuals
839 Tissue transglutaminase 2 (TG2) enzyme activity
524: Gluten-driven immune activation leading to celiac disease in genetically predisposed individuals
840 Redox status
504: SULT1E1 inhibition leading to uterine adenocarcinoma via increased estrogen availability at target organ level
842 CuO nanoparticles
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
843 Elesclomol
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
844 Wilson's disease
590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism