Prototypical Stressors

Showing 1 to 25 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

874	Benzo(g,h,i)perylene	Benzo(g,h,i)perylene, CAS-RN: 191-24-2, DTXSID5023908	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
873	Dibenz(a,h)anthracene	Dibenz(a,h)anthracene, CAS-RN: 53-70-3, DTXSID9020409	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
872	Indeno(1,2,3-cd)pyrene	Indeno(1,2,3-cd)pyrene, CAS-RN: 193-39-5, DTXSID8024153	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
871	Fluoranthene	Fluoranthene, CAS-RN: 206-44-0, DTXSID3024104	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
870	Fluorene	Fluorene, CAS-RN: 86-73-7, DTXSID8024105	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
869	Acenaphthylene	Acenaphthylene, CAS-RN: 208-96-8, DTXSID3023845	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
868	Acenaphthene	Acenaphthene, CAS-RN: 83-32-9, DTXSID3021774	2 AOPs 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
867	2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine	2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine, CAS-RN: 105650-23-5, DTXSID3037628	644: Bulky DNA adducts leading to chromosomal aberrations and mutations
866	3-Methylcholanthrene	3-Methylcholanthrene, CAS-RN: 56-49-5, DTXSID0020862	644: Bulky DNA adducts leading to chromosomal aberrations and mutations
865	5-Methylchrysene	5-Methylchrysene, CAS-RN: 3697-24-3, DTXSID6063143	644: Bulky DNA adducts leading to chromosomal aberrations and mutations
864	Chrysene	Chrysene, CAS-RN: 218-01-9, DTXSID0022432	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
863	Benz(a)anthracene	Benz(a)anthracene, CAS-RN: 56-55-3, DTXSID5023902	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
862	Pyrene	Pyrene, CAS-RN: 129-00-0, DTXSID3024289	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
861	Anthracene	Anthracene, CAS-RN: 120-12-7, DTXSID0023878	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
860	Naphthalene	Naphthalene, CAS-RN: 91-20-3, DTXSID8020913	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
859	Benzo(b)fluoranthene	Benzo(b)fluoranthene, CAS-RN: 205-99-2, DTXSID0023907	3 AOPs 644: Bulky DNA adducts leading to chromosomal aberrations and mutations 645: Binding and activation of AhR lead to cardiovascular aging 646: Binding and activation of AhR/PPARγ lead to lipid metabolism disorders
858	Carboplatin	Carboplatin, CAS-RN: 41575-94-4, DTXSID3046742	472: DNA adduct formation leading to kidney failure
857	Oxaliplatin	Oxaliplatin, CAS-RN: 61825-94-3, DTXSID0036760	472: DNA adduct formation leading to kidney failure
856	Chlorotoluron	Chlorotoluron, CAS-RN: 15545-48-9, DTXSID8052853	567: Binding to plastoquinone B site leading to decreased population growth rate via photosystem II inhibition
855	Metribuzin	Metribuzin, CAS-RN: 21087-64-9, DTXSID6024204	567: Binding to plastoquinone B site leading to decreased population growth rate via photosystem II inhibition
854	ML385		615: Suppression of Keap1 cysteine oxidation leading to liver inflammation
853	Brusatol		615: Suppression of Keap1 cysteine oxidation leading to liver inflammation
852	Tebufenpyrad	Tebufenpyrad, CAS-RN: 119168-77-3, DTXSID0034223	3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits
851	Pyrimidifen	Pyrimidifen, CAS-RN: 105779-78-0, DTXSID9057925	3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits
850	Deguelin	Deguelin, CAS-RN: 522-17-8, DTXSID10200231	3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits