Prototypical Stressors

Showing 326 to 350 of 874 Prototypical Stressors

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ID Prototypical Stressor Name Associated Chemical(s): Name, CAS-RN, DTXSID Associated AOPs
614 iguratimod
  • Iguratimod, CAS-RN: 123663-49-0, DTXSID0048971
277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
612 curcumin
  • Curcumin, CAS-RN: 458-37-7, DTXSID8031077
277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
611 Pralnacasan (VX-740, HMR3480)
277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
609 Belnacasan (VX-765)
277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
605 Emodin
  • Emodin, CAS-RN: 518-82-1, DTXSID5025231
263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
604 Dinoseb
  • Dinoseb, CAS-RN: 88-85-7, DTXSID3020207
263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
810 Forskolin
558: Phosphodiesterase inhibition leading to heart failure
813 Donepezil
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
814 Neostigmine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
815 Pyridostigmine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
602 Carbonyl cyanide m-chlorophenyl hydrazone
263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
601 Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
819 Carbaryl
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
822 Carbofuran
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
586 RB1
315: Inhibition of JAK3 leading to impairment of T-Cell Dependent Antibody Response
593 Polyoxin D
360: Chitin synthase 1 inhibition leading to mortality
770 Polyvinyl chloride
  • Polyvinyl chloride, CAS-RN: 9002-86-2, DTXSID5025940
505: Reactive Oxygen Species (ROS) formation leads to cancer via inflammation pathway
595 Captan
  • Captan, CAS-RN: 133-06-2, DTXSID9020243
360: Chitin synthase 1 inhibition leading to mortality
821 Physostigmine
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
820 Aldicarb
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
598 Exemestane
  • Exemestane, CAS-RN: 107868-30-4, DTXSID5023037
346: Aromatase inhibition leads to male-biased sex ratio via impacts on gonad differentiation
599 Stressor:292 Clotrimazole
346: Aromatase inhibition leads to male-biased sex ratio via impacts on gonad differentiation
816 Diazinon
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
817 Sarin
559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
809 Catecholamines
558: Phosphodiesterase inhibition leading to heart failure