Prototypical Stressors

Showing 651 to 675 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

222	MPP+		3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits
221	Small molecules: ITB3, ITB4, ITB5, ITB9		None
220	5-(N,N-hexamethylene) amiloride (HMA)		None
219	Econazole		None
218	metofluthrin	Metofluthrin, CAS-RN: 240494-70-6, DTXSID4034738	107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
217	kinoprene	Kinoprene, CAS-RN: 42588-37-4, DTXSID3032624	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
216	(7S)-Hydroprene	(7S)-Hydroprene, CAS-RN: 65733-18-8, DTXSID6035784	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
215	pyriproxyfen	Pyriproxyfen, CAS-RN: 95737-68-1, DTXSID1032640	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
214	DIOFENOLAN	Diofenolan, CAS-RN: 63837-33-2, DTXSID2041884	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
213	fenoxycarb	Fenoxycarb, CAS-RN: 72490-01-8, DTXSID7032393	201: Juvenile hormone receptor agonism leading to male offspring induction associated population decline
212	iopanoic acid	Iopanoic acid, CAS-RN: 96-83-3, DTXSID6023159	155: Deiodinase 2 inhibition leading to increased mortality via reduced posterior swim bladder inflation
211	Fenofibrate	Fenofibrate, CAS-RN: 49562-28-9, DTXSID2029874	2 AOPs 37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents 323: PPARalpha Agonism Leading to Decreased Viable Offspring via Decreased 11-Ketotestosterone
210	Bezafibrate	Bezafibrate, CAS-RN: 41859-67-0, DTXSID3029869	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
209	trichloroacetic acid	Trichloroacetic acid, CAS-RN: 76-03-9, DTXSID1021378	None
208	Gemfibrozil	Gemfibrozil, CAS-RN: 25812-30-0, DTXSID0020652	2 AOPs 37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents 323: PPARalpha Agonism Leading to Decreased Viable Offspring via Decreased 11-Ketotestosterone
207	ciprofibrate	Ciprofibrate, CAS-RN: 52214-84-3, DTXSID8020331	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
206	Nafenopin	Nafenopin, CAS-RN: 3771-19-5, DTXSID8020911	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
205	pirinixic acid	Pirinixic acid, CAS-RN: 50892-23-4, DTXSID4020290	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
204	Tetrahydrocannabinol	1-trans-delta-9-Tetrahydrocannabinol, CAS-RN: 1972-08-3, DTXSID6021327	None
203	Fluvoxamine	Fluvoxamine, CAS-RN: 54739-18-3, DTXSID2044002	2 AOPs 195: 5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase 203: 5-hydroxytryptamine transporter inhibition leading to decreased reproductive success and population decline
202	Fluoxetine		3 AOPs 195: 5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase 97: 5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to population decline 203: 5-hydroxytryptamine transporter inhibition leading to decreased reproductive success and population decline
201	3-[3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2-benzopyrone		187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage
200	pindone	Pindone, CAS-RN: 83-26-1, DTXSID1025930	187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage
199	diphacinone	Diphacinone, CAS-RN: 82-66-6, DTXSID4032378	187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage
198	chlorophacinone	Chlorophacinone, CAS-RN: 3691-35-8, DTXSID2032348	187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage