Prototypical Stressors

Showing 776 to 800 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

97	Valproate		212: Histone deacetylase inhibition leading to testicular atrophy
96	Phenytoin		None
95	Amiodarone	Amiodarone, CAS-RN: 1951-25-3, DTXSID7022592	2 AOPs 555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure 560: Inhibition of Funny current (If) leading to Arrhythmias
94	Tetrodotoxin		553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
93	Topiramate	Topiramate, CAS-RN: 97240-79-4, DTXSID8023688	None
92	Carbamazepine	Carbamazepine, CAS-RN: 298-46-4, DTXSID4022731	None
91	Sodium (4-fluoro-2-{[(1S)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide		None
90	Oxytetracycline hydrochloride	Oxytetracycline hydrochloride, CAS-RN: 2058-46-0, DTXSID5021097	None
89	2058-46-0		None
88	Tetraconazole	Tetraconazole, CAS-RN: 112281-77-3, DTXSID8034956	None
87	3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]-1H-pyrazole		None
86	Celecoxib	Celecoxib, CAS-RN: 169590-42-5, DTXSID0022777	177: Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality
85	169590-42-5		None
84	1-Chloro-4-nitrobenzene	1-Chloro-4-nitrobenzene, CAS-RN: 100-00-5, DTXSID5020281	None
83	Emamectin benzoate	Emamectin benzoate, CAS-RN: 155569-91-8, DTXSID0034566	2 AOPs 161: Glutamate-gated chloride channel activation leading to neurotransmission inhibition associated mortality 160: Ionotropic gamma-aminobutyric acid receptor activation mediated neurotransmission inhibition leading to mortality
82	Ibuprofen	Ibuprofen, CAS-RN: 15687-27-1, DTXSID5020732	177: Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality
81	Aryltrifluoroborates		54: Inhibition of Na+/I- symporter (NIS) leads to learning and memory impairment
80	N-methyl Carbamates		405: Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function
79	Sulfamethazine	Sulfamethazine, CAS-RN: 57-68-1, DTXSID6021290	None
78	4-propoxyphenol		None
77	4-Nonylphenol	4-Nonylphenol, CAS-RN: 104-40-5, DTXSID5033836	None
76	Genistein	Genistein, CAS-RN: 446-72-0, DTXSID5022308	167: Early-life estrogen receptor agonism leading to endometrial adenosquamous carcinoma via promotion of sine oculis homeobox 1 progenitor cells
75	Daidzein	7,4'-Dihydroxyisoflavone, CAS-RN: 486-66-8, DTXSID9022310	None
74	2,2',4,4'-Tetrahydroxybenzophenone	2,2',4,4'-Tetrahydroxybenzophenone, CAS-RN: 131-55-5, DTXSID5041306	2 AOPs 175: Thyroperoxidase inhibition leading to altered amphibian metamorphosis 152: Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity
73	131-55-5		None