Key Event Components

  • Key Event Components (KECs) are used to describe Key Events (KEs) in a computable way, by defining an action, processes, and object term that maps to controlled vocabulary and ontology terms.
  • KECs on this page can be filtered by the action, process, and object terms, as well as by source ontologies.
  • Link to source ontology terms are provided in cases where the URL was available when the ontology terms were added to the AOP-Wiki database.
  • A complete list of all KECs is available in TSV format on the Downloads Page.
Showing 1126 to 1146 of 1146 KECs
Clear Table Filters
ID Action Process Object Associated Key Events (KEs)
266 increased apoptotic process (GO:0006915)
273 increased abnormal fetal Leydig cell differentiation (MP:0013603)
274 increased Testicular dysgenesis (HP:0008715)
293 decreased hormone secretion (GO:0046879) Gonadotropin Releasing Hormone (MESH:D007987)
299 increased abnormal chromosome number (MP:0004023)
320 decreased feeding behavior (NBO:0000079)
504 increased thyroxine (CHEBI:30660)
622 increased dermatitis (MP:0001194)
928 occurrence receptor binding (GO:0005102)
16 increased mortality (MESH:D009026)
26 decreased fatty acid beta-oxidation (GO:0006635) fatty acid (CHEBI:35366)
83 decreased population growth rate (PCO:0000008)
119 decreased ATP biosynthetic process (GO:0006754) ATP (CHEBI:15422)
277 decreased sperm (CL:0000019)
450 occurrence autophagic cell death (GO:0048102)
82 increased paralysis (MP:0000753)
93 decreased testosterone biosynthetic process (GO:0061370) testosterone (CHEBI:17347)
128 increased inflammatory response (GO:0006954)
100 decreased fertility (MESH:D005298)
366 increased Adenoma (MESH:D000236)
367 increased Carcinoma (MESH:D002277)