Key Event Components

  • Key Event Components (KECs) are used to describe Key Events (KEs) in a computable way, by defining an action, processes, and object term that maps to controlled vocabulary and ontology terms.
  • KECs on this page can be filtered by the action, process, and object terms, as well as by source ontologies.
  • Link to source ontology terms are provided in cases where the URL was available when the ontology terms were added to the AOP-Wiki database.
  • A complete list of all KECs is available in TSV format on the Downloads Page.
Showing 1126 to 1147 of 1147 KECs
Clear Table Filters
ID Action Process Object Associated Key Events (KEs)
1038 increased cell activation involved in immune response (GO:0002263) Peyer's patch B cell (CL:0002402) None
1039 increased cell activation involved in immune response (GO:0002263) B cell (CL:0000236) None
1040 increased Celiac disease (HP:0002608) intestinal epithelial cell (CL:0002563) None
1041 increased T cell activation involved in immune response (GO:0002286) T cell (CL:0000084) None
1042 increased T cell migration (GO:0072678) T cell (CL:0000084) None
1043 increased dendritic cell migration (GO:0036336) professional antigen presenting cell (CL:0000145) None
1044 increased immune system process (GO:0002376) None
1045 decreased insulin-induced gene 1 protein (PR:000009056) None
1066 increased hormone activity (GO:0005179) None
1067 increased hormone activity (GO:0005179) tissue (UBERON:0000479) None
1068 occurrence cell activation involved in immune response (GO:0002263) None
1078 increased serotonin receptor signaling pathway (GO:0007210) Serotonin receptor (FMA:67372) None
1092 arrested androgen receptor signaling pathway (GO:0030521) androgen receptor (PR:000004191) None
1093 decreased androgen receptor signaling pathway (GO:0030521) androgen receptor (PR:000004191) None
1100 increased NMDA glutamate receptor activity (GO:0004972) None
1103 increased homeobox protein SIX1 (PR:000014896) None
1123 decreased regulation of vascular permeability (GO:0043114) None
1125 decreased mRNA transcription (GO:0009299) undifferentiated genital tubercle (UBERON:0005876) None
1131 decreased fibroblast growth factor 2 (PR:000007489) None
1136 decreased neuropeptide signaling pathway (GO:0007218) Metastin (CHEBI:80304) None
1142 increased female gonad development (GO:0008585) female organism (UBERON:0003100) None
1143 increased female gonad development (GO:0008585) None