| 1033 |
increased |
androgen biosynthetic process
(GO:0006702)
|
17beta-hydroxy-5alpha-androstan-3-one
(CHEBI:16330)
|
2273: Dihydrotestosterone (DHT) levels, increased
|
| 1046 |
increased |
increased circulating total protein level
(MP:0005568)
|
sterol regulatory element-binding protein 2
(PR:000015612)
|
2269: Increased, Sterol Regulatory Element Binding Protein 2 (SREBP2) protein expression
|
| 1047 |
decreased |
decreased circulating total protein level
(MP:0005567)
|
insulin-induced gene 1 protein
(PR:000009056)
|
2268: Decreased, insulin-induced gene 1 (INSIG1) protein activity
|
| 1048 |
increased |
increased circulating LDL cholesterol level
(MP:0000182)
|
low-density lipoprotein cholesterol
(CHEBI:47774)
|
2271: Increased, plasma low-density lipoprotein (LDL) cholesterol
|
| 1049 |
increased |
increased circulating total protein level
(MP:0005568)
|
proprotein convertase subtilisin/kexin type 9
(PR:000012440)
|
2276: Increased, protein expression of proprotein convertase subtilisin/kexin type 9 (PCSK9)
|
| 1050 |
pathological |
Celiac disease
(HP:0002608)
|
intestinal epithelial cell
(CL:0002563)
|
2257: Celiac disease
|
| 1051 |
occurrence |
antigen presentation trait
(VT:0001835)
|
Human leukocyte antigen complex
(FMA:84795)
|
2252: Human leukocyte antigen DQ2/8-gluten complexes, formation
|
| 1052 |
occurrence |
gene conversion
(GO:0035822)
|
alpha-beta T cell receptor complex
(GO:0042105)
|
2253: Gluten-reactive T cell receptors, generation
|
| 1053 |
occurrence |
gene conversion of immunoglobulin genes
(GO:0002206)
|
B cell receptor complex
(GO:0019815)
|
2254: Gluten-reactive and transglutaminase 2 reactive B cell receptors, generation
|
| 1054 |
occurrence |
T cell migration
(GO:0072678)
|
T cell
(CL:0000084)
|
2275: Gluten reactive adaptive T-cells with antigen presenting cells, co-localization
|
| 1055 |
occurrence |
dendritic cell migration
(GO:0036336)
|
professional antigen presenting cell
(CL:0000145)
|
2275: Gluten reactive adaptive T-cells with antigen presenting cells, co-localization
|
| 1056 |
occurrence |
immune system process
(GO:0002376)
|
|
2255: Innate immune response, activation
|
| 1057 |
occurrence |
T cell activation involved in immune response
(GO:0002286)
|
T cell
(CL:0000084)
|
2260: Gluten-reactive CD4+ T cells, activation
|
| 1058 |
occurrence |
B cell activation involved in immune response
(GO:0002312)
|
B cell
(CL:0000236)
|
2256: Gluten-reactive B cells and transglutaminase 2-reactive B cells, activation
|
| 1059 |
decreased |
retinoic acid biosynthetic process
(GO:0002138)
|
retinal dehydrogenase 1
(PR:000003920)
|
1880: Decreased, ALDH1A (RALDH) enzyme activity
|
| 1060 |
decreased |
retinoic acid biosynthetic process
(GO:0002138)
|
all-trans-retinoic acid
(CHEBI:15367)
|
1881: Decreased, all-trans retinoic acid (atRA) concentration
|
| 1061 |
decreased |
ovarian follicle development
(GO:0001541)
|
ovarian follicle
(UBERON:0001305)
|
1883: Decreased, size of the ovarian reserve
|
| 1062 |
disrupted |
meiosis I
(GO:0007127)
|
oocyte
(CL:0000023)
|
1882: Disrupted, initiation of meiosis of oogonia in the ovary
|
| 1063 |
disrupted |
ovulation cycle
(GO:0042698)
|
ovarian follicle
(UBERON:0001305)
|
405: disrupted, ovarian cycle
|
| 1064 |
decreased |
fertilization
(GO:0009566)
|
fertility
(MESH:D005298)
|
406: decreased, Fertility
|
| 1065 |
decreased |
ovulation
(GO:0030728)
|
Ovum
(FMA:67343)
|
1695: Impaired ovulation
|
| 1069 |
abnormal |
cell redox homeostasis
(GO:0045454)
|
|
2299: Altered, Redox Homeostasis
|
| 1070 |
disrupted |
glucose metabolic process
(GO:0006006)
|
|
2300: Disruption, Glucolipid metabolism
|
| 1071 |
disrupted |
abnormal lipid metabolism
(MP:0013245)
|
|
2300: Disruption, Glucolipid metabolism
|
| 1072 |
abnormal |
behavior
(GO:0007610)
|
|
2301: Abnormal, Behavior
|