Key Event Components

  • Key Event Components (KECs) are used to describe Key Events (KEs) in a computable way, by defining an action, processes, and object term that maps to controlled vocabulary and ontology terms.
  • KECs on this page can be filtered by the action, process, and object terms, as well as by source ontologies.
  • Link to source ontology terms are provided in cases where the URL was available when the ontology terms were added to the AOP-Wiki database.
  • A complete list of all KECs is available in TSV format on the Downloads Page.
Showing 1051 to 1075 of 1152 KECs
Clear Table Filters
ID Action Process Object Associated Key Events (KEs)
993 increased energy deposition event (RBO:00015021) 1686: Deposition of Energy
995 decreased neurogenesis (GO:0022008) 2098: Increase, Abnormal Neural Remodeling
996 increased demyelination (MP:0000921)
997 increased neuron death (GO:0070997) 2098: Increase, Abnormal Neural Remodeling
998 increased cell surface receptor signaling pathway (GO:0007166)
999 abnormal cell differentiation (GO:0030154) 2245: Altered Cell Differentiation Signaling
1001 decreased bone mineralization (GO:0030282) 2090: Increase, Bone Remodeling
1002 occurrence positive regulation of bone resorption (GO:0045780) 2090: Increase, Bone Remodeling
1003 occurrence abnormal bone remodeling (MP:0002998) 2090: Increase, Bone Remodeling
1004 decreased osteoblast differentiation (GO:0001649) 2089: Altered Bone Cell Homeostasis
1005 increased osteoclast differentiation (GO:0030316) 2089: Altered Bone Cell Homeostasis
1007 occurrence decreased trabecular bone volume (MP:0010879) 2091: Occurrence, Bone Loss
1008 occurrence decreased bone mineral density (MP:0000063) 2091: Occurrence, Bone Loss
1009 increased endothelial cell apoptotic process (GO:0072577) 2068: Increase, Endothelial Dysfunction
1010 increased protein modification process (GO:0036211) 2081: Increased Modified Proteins
1023 increased CNS demyelination (HP:0007305) 2266: Demyelination, increased
1024 decreased decreased circulating total protein level (MP:0005567) None
1025 increased increased circulating total protein level (MP:0005568) None
1026 increased cholesterol biosynthetic process (GO:0006695) 2270: Increased, cholesterol synthesis enzymes
1031 increased Immunosuppression (IDO:0000610) 984: Impairment, T-cell dependent antibody response
1044 increased immune system process (GO:0002376) None
1056 occurrence immune system process (GO:0002376) 2255: Innate immune response, activation
1066 increased hormone activity (GO:0005179) None
1068 occurrence cell activation involved in immune response (GO:0002263) None
1069 abnormal cell redox homeostasis (GO:0045454) 2299: Altered, Redox Homeostasis