Aop:183

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Status

This is a legacy representation of this AOP. Please see the current version here:

https://aopwiki.org/aops/183


AOP Title

Nosema infection increases energetic demands leading to colony loss/failure
Short name: Nosema to energy to colony loss/failure

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Status

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Under development: Do not distribute or cite.

This AOP page was last modified on 12/11/2016.

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Abstract

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Summary of the AOP

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Molecular Initiating Event

Molecular Initiating Event Support for Essentiality

Key Events

Event Support for Essentiality
Energetic demands and therefore metabolic stress, Increased
Foraging activity and behavior, Abnormal
Colony, Weakened

Adverse Outcome

Adverse Outcome
Colony, Death/Failure

Relationships Among Key Events and the Adverse Outcome

Event Description Triggers Weight of Evidence Quantitative Understanding
Energetic demands and therefore metabolic stress, Increased Directly Leads to Foraging activity and behavior, Abnormal
Foraging activity and behavior, Abnormal Directly Leads to Colony, Weakened
Colony, Weakened Directly Leads to Colony, Death/Failure

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Life Stage Applicability

Life Stage Evidence Links

Taxonomic Applicability

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Sex Applicability

Sex Evidence Links

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Overall Assessment of the AOP

Domain of Applicability

Life Stage Applicability, Taxonomic Applicability, Sex Applicability
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Essentiality of the Key Events

Molecular Initiating Event Summary, Key Event Summary
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Weight of Evidence Summary

Summary Table
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Quantitative Considerations

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Considerations for Potential Applications of the AOP (optional)

References