Key Event Overview
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AOPs Including This Key Event
|AOP Name||Event Type||Essentiality|
|Acetylcholinesterase inhibition leading to acute mortality||KE||Weak|
|Sodium channel inhibition leading to congenital malformations||KE|
Level of Biological Organization
How this Key Event works
The rhythm of conduction between the atria and ventricles of the heart regulate heart rate. Disruption of heart rhythm can lead to reduced heart rate.
How it is Measured or Detected
Atrioventricular block and heart rate can be measured with an electrocardiogram (ECG).
Evidence Supporting Taxonomic Applicability
This key event is only relevant to organisms with a heart.