Relationship:432

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Key Event Relationship Overview

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Description of Relationship

Upstream Event Downstream Event/Outcome
Atrioventricular block and bradycardia, Increased Mortality, Increased

AOPs Referencing Relationship

AOP Name Type of Relationship Weight of Evidence Quantitative Understanding
Acetylcholinesterase inhibition leading to acute mortality Directly Leads to Weak Weak

Taxonomic Applicability

Name Scientific Name Evidence Links

How Does This Key Event Relationship Work

Severe arrhythmias or a heart rate insufficient to supply oxygen to the rest of the body can result in mortality.

Weight of Evidence

Biological Plausibility

Empirical Support for Linkage

Not assembled.

Uncertainties or Inconsistencies

Quantitative Understanding of the Linkage

Not evaluated.

Evidence Supporting Taxonomic Applicability

References