Key Event Overview
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AOPs Including This Key Event
|AOP Name||Event Type||Essentiality|
|Cyclooxygenase inhibition leading reproductive failure||KE|
Level of Biological Organization
How this Key Event works
Do NOT enter any biological descriptions for this key event! This key event is intended as a placeholder for cases where there is a known gap of knowledge that should be noted in an AOP. If you would like to include information specific to your AOP when using this key event, you can include that information on the key event relationship pages that connect this key event to the key events in your AOP.
How it is Measured or Detected
Methods that have been previously reviewed and approved by a recognized authority should be included in the Overview section above. All other methods, including those well established in the published literature, should be described here. Consider the following criteria when describing each method: 1. Is the assay fit for purpose? 2. Is the assay directly or indirectly (i.e. a surrogate) related to a key event relevant to the final adverse effect in question? 3. Is the assay repeatable? 4. Is the assay reproducible?