Difference between revisions of "Event:269"

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.ui-menu .ui-menu-item a
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== Event Title ==
        {
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<div id='longTitle' class='Title'>Sustained Cell Proliferation, Induction</div>
            display: block;
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<div id='shortTitle' class='Title2'>Short name: Sustained Cell Proliferation, Induction</div>
            padding: 1px 1px 1px 1px;
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            text-decoration: none;
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            cursor: pointer;
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</style>
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<link type='text/css' rel='stylesheet' href='/aopwiki/extensions/jquery-ui-1.9.2/themes/base/jquery-ui.css'>
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== Key Event Overview ==
<script type="text/javascript" src="/aopwiki/extensions/jquery-ui-1.9.2/ui/jquery-ui.js"></script>
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Please follow link to [//{{SERVERNAME}}/events/{{PAGENAMEE}} widget page] to edit this section.
<script type="text/javascript" src="/aopwiki/extensions/EPA/Common_Functions.js"></script>
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<script type="text/javascript" src="/aopwiki/extensions/EPA/MOA_Species.js"></script>
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<span style="color:#FF0000">'''If you manually enter text in this section, it will get automatically altered or deleted in subsequent edits using the widgets.'''</span>
<script type="text/javascript" src="/aopwiki/extensions/EPA/MOA_Chemicals.js"></script>
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<script type="text/javascript" src="/aopwiki/extensions/EPA/MOA_Key_Event.js"></script>
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<script type="text/javascript" src="/aopwiki/extensions/EPA/MOA_Biological_Organization.js"></script>
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</html>
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== Key Event Overview ==
 
<div id="hideMsg2" style='display:none'>
 
Currently adding your chemical.
 
Processing(<span>0</span>)
 
<p id="problem">The servers seem to be running slow.  Your patience is appreciated.</p>
 
<p id="error">Oops! An error has most likely occurred. Reload the page and try again or report the problem.</p>
 
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=== AOPs Including This Key Event ===
 
=== AOPs Including This Key Event ===
  
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!AOP Name
 
!AOP Name
!Molecular Initiating Event?
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!Event Type
 
!Essentiality
 
!Essentiality
  
 
|-
 
|-
  
|[[Inhibition of iNOS, hepatotoxicity, and regenerative proliferation leading to liver tumors]]||No||[[Sustained Cell Proliferation, Induction#How it is Measured or Detected|Strong]]
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|[[Aop:32|Inhibition of iNOS, hepatotoxicity, and regenerative proliferation leading to liver tumors]]||KE||
  
 
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|-
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=== Taxonomic Applicability ===
 
=== Taxonomic Applicability ===
 
<html>
 
<button id="SpeciesList">Add Species from list</button>
 
</html>
 
<div id="popbox6" title='Add a Record' style='display:none'>
 
<html>
 
<span id="chosen2" style="float:left"> Common Name </span><span class="ui-icon ui-icon-info" title="commonly used name for species e.g. dog, cat, fish"></span>
 
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<input type=text id="specInput" style="float:left"></input>
 
<button id="SubNext">Search</button>
 
<button id="EditNext">Search</button>
 
</br>
 
</br>
 
<span id="chosen1" style="float:left"> Scientific Name</span><span class="ui-icon ui-icon-info" title="Applicable NCBI scientific taxonomy names for the suggested species"></span>
 
</br>
 
<select id="scientificSpecies"></select>
 
</br>
 
</br>
 
<span id="chosen3" style="float:left"> Evidence</span><span class="ui-icon ui-icon-info" title="How strong the evidence is for this species"></span>
 
</br>
 
<select id="weightSpec">
 
  <option></option>
 
  <option>Strong</option> 
 
  <option>Moderate</option>
 
  <option>Weak</option> 
 
</select>
 
</br>
 
</br>
 
<button id="SubSpec">Submit</button>
 
<button id="EditSpec">Submit</button>
 
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Attempting to compile scientific names.
 
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{|class="wikitable sortable" id="Specproof"
  
!Common Name
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!Name
 
!Scientific Name
 
!Scientific Name
 
!Evidence
 
!Evidence
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=== Level of Biological Organization ===
 
=== Level of Biological Organization ===
<html>
 
<button id="bioOrgButton">Add Biological Organization from list</button>
 
</br>
 
<select id="bioOrgDropdown">
 
  <option></option>
 
  <option>Molecular</option> 
 
  <option>Cellular</option>
 
  <option>Tissue</option>
 
  <option>Organ</option>
 
  <option>Individual</option> 
 
</select>
 
<button id="bioOrgSubmit">Submit</button>
 
</html>
 
  
 
{|class="wikitable sortable" id="BioProof"
 
{|class="wikitable sortable" id="BioProof"

Latest revision as of 03:52, 17 January 2016



Event Title

Sustained Cell Proliferation, Induction
Short name: Sustained Cell Proliferation, Induction

Key Event Overview

Please follow link to widget page to edit this section.

If you manually enter text in this section, it will get automatically altered or deleted in subsequent edits using the widgets.

AOPs Including This Key Event

AOP Name Event Type Essentiality
Inhibition of iNOS, hepatotoxicity, and regenerative proliferation leading to liver tumors KE

Taxonomic Applicability

Name Scientific Name Evidence Links

Level of Biological Organization

Biological Organization

How this Key Event works

How it is Measured or Detected

Methods that have been previously reviewed and approved by a recognized authority should be included in the Overview section above. All other methods, including those well established in the published literature, should be described here. Consider the following criteria when describing each method: 1. Is the assay fit for purpose? 2. Is the assay directly or indirectly (i.e. a surrogate) related to a key event relevant to the final adverse effect in question? 3. Is the assay repeatable? 4. Is the assay reproducible?

Evidence Supporting Taxonomic Applicability

References