Event:298

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Key Event Overview

AOPs Including This Key Event

AOP Name Molecular Initiating Event? Essentiality
VEGF Inhibition Leading to Vascular Disruption During Embryonic Development No

Taxonomic Applicability

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Common Name Scientific Name Evidence Links

Previously Approved or Guideline Methods

Level of Biological Organization

How this Key Event works

How it is Measured or Detected

Methods that have been previously reviewed and approved by a recognized authority should be included in the Overview section above. All other methods, including those well established in the published literature, should be described here. Consider the following criteria when describing each method: 1. Is the assay fit for purpose? 2. Is the assay directly or indirectly (i.e. a surrogate) related to a key event relevant to the final adverse effect in question? 3. Is the assay repeatable? 4. Is the assay reproducible?

Evidence Supporting Taxonomic Applicability

References