Event:588

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Event Title

predation, Increased

Key Event Overview

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AOPs Including This Key Event

AOP Name Event Type Essentiality
sodium channel inhibition leading to increased predation AO
Sodium channel inhibition leading to reduced survival AO
Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival KE
5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to decreased shelter seeking and increased predation AO
Histamine (H2) receptor antagonism leading to reduced survival AO

Taxonomic Applicability

Name Scientific Name Evidence Links

Affected Organs

Synonym Scientific Name Evidence Links

Level of Biological Organization

Biological Organization

How this Key Event works

How it is Measured or Detected

Methods that have been previously reviewed and approved by a recognized authority should be included in the Overview section above. All other methods, including those well established in the published literature, should be described here. Consider the following criteria when describing each method: 1. Is the assay fit for purpose? 2. Is the assay directly or indirectly (i.e. a surrogate) related to a key event relevant to the final adverse effect in question? 3. Is the assay repeatable? 4. Is the assay reproducible?

Evidence Supporting Taxonomic Applicability

References