Difference between revisions of "Relationship:1000"

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|[[Aop:4|Ecdysone receptor (EcR) activation leading to mortality in ''Daphnia magna'']]||Directly Leads to||[[Relationship:1000#Weight of Evidence|Moderate]]||[[Relationship:1000#Quantitative Understanding of the Linkage|Weak]]
  
 
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Revision as of 17:00, 13 May 2016


Key Event Relationship Overview

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Description of Relationship

Upstream Event Downstream Event/Outcome
Secretion of ecdysis triggering hormone (ETH), Decreased Incomplete ecdysis, Increased

AOPs Referencing Relationship

AOP Name Type of Relationship Weight of Evidence Quantitative Understanding
Ecdysone receptor (EcR) activation leading to mortality in Daphnia magna Directly Leads to Moderate Weak

Taxonomic Applicability

Name Scientific Name Evidence Links

How Does This Key Event Relationship Work

Weight of Evidence

Biological Plausibility

Empirical Support for Linkage

Include consideration of temporal concordance here

Uncertainties or Inconsistencies

Quantitative Understanding of the Linkage

Is it known how much change in the first event is needed to impact the second? Are there known modulators of the response-response relationships? Are there models or extrapolation approaches that help describe those relationships?

Evidence Supporting Taxonomic Applicability

References