Relationship:1225
Contents
Key Event Relationship Overview
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Description of Relationship
Upstream Event | Downstream Event/Outcome |
---|---|
water pumping, Increased | Spawning , premature |
AOPs Referencing Relationship
AOP Name | Type of Relationship | Weight of Evidence | Quantitative Understanding |
---|---|---|---|
5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to population decline | Directly Leads to |
Taxonomic Applicability
Name | Scientific Name | Evidence | Links |
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How Does This Key Event Relationship Work
In bivalves, sperm and oocytes are released via the siphon. This release is dependent upon the pumping action to move water forcefully out of the organism, carrying the gametes. Increased flow rate due to vigorous movement of cilia withing the gill filaments contributes to this pumping out of gametes (Carrol and Catapane, 2007; Gainey et al., 2003). The musculature within the gill filaments is under serotonergic or dopaminergic-serotinergic control.
Weight of Evidence
Biological Plausibility
Empirical Support for Linkage
Include consideration of temporal concordance here
Uncertainties or Inconsistencies
Quantitative Understanding of the Linkage
Is it known how much change in the first event is needed to impact the second? Are there known modulators of the response-response relationships? Are there models or extrapolation approaches that help describe those relationships?