Difference between revisions of "Relationship:276"
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== Key Event Relationship Overview == | == Key Event Relationship Overview == | ||
[[Category:KE Relationship]] | [[Category:KE Relationship]] | ||
+ | Please follow link to [//{{SERVERNAME}}/relationships/{{PAGENAMEE}} widget page] to edit this section. | ||
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+ | <span style="color:#FF0000">'''If you manually enter text in this section, it will get automatically altered or deleted in subsequent edits using the widgets.'''</span> | ||
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=== Description of Relationship === | === Description of Relationship === | ||
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− | |[[Reactive oxygen species, Production]]||[[Oxidative | + | |[[Event:249|Reactive oxygen species, Production]]||[[Event:209|Oxidative Stress, Increase]] |
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− | |[[Cholestatic Liver Injury induced by Inhibition of the Bile Salt Export Pump (ABCB11)]]||Directly Leads to||[[ | + | |[[Aop:27|Cholestatic Liver Injury induced by Inhibition of the Bile Salt Export Pump (ABCB11)]]||Directly Leads to||[[Relationship:276#Weight of Evidence|Very Strong]]|| |
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=== Taxonomic Applicability === | === Taxonomic Applicability === | ||
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{|class="wikitable sortable" id="Specproof" | {|class="wikitable sortable" id="Specproof" | ||
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!Scientific Name | !Scientific Name | ||
!Evidence | !Evidence |
Latest revision as of 04:01, 17 January 2016
Contents
Key Event Relationship Overview
Please follow link to widget page to edit this section.
If you manually enter text in this section, it will get automatically altered or deleted in subsequent edits using the widgets.
Description of Relationship
Upstream Event | Downstream Event/Outcome |
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Reactive oxygen species, Production | Oxidative Stress, Increase |
AOPs Referencing Relationship
AOP Name | Type of Relationship | Weight of Evidence | Quantitative Understanding |
---|---|---|---|
Cholestatic Liver Injury induced by Inhibition of the Bile Salt Export Pump (ABCB11) | Directly Leads to | Very Strong |
Taxonomic Applicability
Name | Scientific Name | Evidence | Links |
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How Does This Key Event Relationship Work
Weight of Evidence
Biological Plausibility
Empirical Support for Linkage
Include consideration of temporal concordance here
Uncertainties or Inconsistencies
Quantitative Understanding of the Linkage
Is it known how much change in the first event is needed to impact the second? Are there known modulators of the response-response relationships? Are there models or extrapolation approaches that help describe those relationships?