Difference between revisions of "Relationship:398"

From AOP-Wiki
Jump to: navigation, search
(unknown rel user updated summary tables from widget page.)
(unknown rel user updated summary tables from widget page.)
 
Line 15: Line 15:
 
|-
 
|-
  
|[[Event:416|Leydig cell , Increase proliferation]]||[[Event:415|Leydig cell , Hyperplasia]]
+
|[[Event:416|Leydig cell , Increase proliferation]]||[[Event:415|Leydig cell, Hyperplasia]]
  
 
|-
 
|-

Latest revision as of 18:06, 2 July 2016


Key Event Relationship Overview

Please follow link to widget page to edit this section.

If you manually enter text in this section, it will get automatically altered or deleted in subsequent edits using the widgets.

Description of Relationship

Upstream Event Downstream Event/Outcome
Leydig cell , Increase proliferation Leydig cell, Hyperplasia

AOPs Referencing Relationship

AOP Name Type of Relationship Weight of Evidence Quantitative Understanding
PPARα activation leading to impaired fertility in adult male rodents Directly Leads to Moderate

Taxonomic Applicability

Name Scientific Name Evidence Links

How Does This Key Event Relationship Work

Weight of Evidence

Biological Plausibility

Empirical Support for Linkage

Include consideration of temporal concordance here

Uncertainties or Inconsistencies

Quantitative Understanding of the Linkage

Is it known how much change in the first event is needed to impact the second? Are there known modulators of the response-response relationships? Are there models or extrapolation approaches that help describe those relationships?

Evidence Supporting Taxonomic Applicability

References