Relationship: 1064
Title
Increased, T4/T3 catabolism leads to Decreased, serum T4/T3
Upstream event
Increased, T4/T3 catabolismDownstream event
Decreased, serum T4/T3
Key Event Relationship Overview
AOPs Referencing Relationship
AOP Name | Adjacency | Weight of Evidence | Quantitative Understanding |
---|---|---|---|
Enhanced hepatic clearance of thyroid hormones leading to thyroid follicular cell adenomas and carcinomas in the rat and mouse | adjacent | High |