API

Stressors

ID Name
2 (2-ethylhexyl) hydrogen phthalate
3 1-Methylsulfonyloxyethane
4 17beta-Estradiol
5 17beta-Trenbolone
6 2(3H)-Benzothiazolethione
7 2-mercaptobenzothiazole
8 Aceytlsalicylic acid
9 Allyl Alcohol
10 Benzo(k)fluoranthene
11 Bis(2-ethylhexyl) phthalate
12 Butyl 4-hydroxybenzoate
13 Carbon tetrachloride
14 Dibutyl phthalate
15 Diclofenac sodium
16 Diethyl nitrosamine
17 Diethyl sulfate
18 Dimethyl nitrosamine
19 Dimethyl sulfate
20 Dioxin and dioxin-like compounds
21 Domoic acid
22 Ethyl methanesulfonate
23 Ethyl nitrosourea
24 Ethyl-N'-nitro-N-nitrosoguanidine
25 Ethylene thiourea
26 Fadrozole
27 Indomethacin
28 Isopropyl methanesulfonate
29 Kainic acid
30 Lead(II)
31 Lead(II) acetate trihydrate
32 Letrozole
33 Maneb
34 Mercaptobenzothiazole
35 Mercuric chloride
36 Mercury
37 Methimazole
38 Methyl methanesulfonate
39 Methyl-l-N'-nitro-N-nitroguanidine
40 Methylmercuric(II) chloride
41 Naproxen
42 Ochratoxin A
43 Organophosphates
44 Paraquat
45 Parathion
46 Phenanthrene
47 Prochloraz
48 Propylthiouracil
49 Resorcinol
50 Rotenone
51 Selected AHR Ligands
52 Spironolactone
53 Thiouracil
54 Trimethyltin chloride
55 Vatalanib
56 Ethylenethiourea
57 Acetaminophen
58 Mercaptobenzole
59 Lead
60 Retinol
61 Aflatoxin B1
62 Benzidine
63 Thioacetamide
64 Mono(2-ethylhexyl) phthalate
65 Di(2-ethylhexyl) phthalate
66 Perchlorate
67 Nitrate
68 Thiocyanate
69 Dysidenin
70 Troglitazone
71 1-CHLORO-2,4- DINITROBENZENE
72 Amitrole
73 131-55-5
74 2,2',4,4'-Tetrahydroxybenzophenone
75 Daidzein
76 Genistein
77 4-Nonylphenol
78 4-propoxyphenol
79 Sulfamethazine
80 N-methyl Carbamates
81 Aryltrifluoroborates
82 Ibuprofen
83 Emamectin benzoate
84 1-Chloro-4-nitrobenzene
85 169590-42-5
86 Celecoxib
87 3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]-1H-pyrazole
88 Tetraconazole
89 2058-46-0
90 Oxytetracycline hydrochloride
91 Sodium (4-fluoro-2-{[(1S)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide
92 Carbamazepine
93 Topiramate
94 Tetrodotoxin
95 Amiodarone
96 Phenytoin
97 Valproate
98 Zonisamide
99 Lidocaine
100 2,4-dinitrotoluene
101 2,6-dinitrotoluene
102 2-amino-4,6-dinitrotoluene
103 Cypermethrin
104 Permethrin
105 Esfenvalerate
106 Tralomethrin
107 Bifenthrin
108 Cyfluthrin
109 Lambda-Cyhalothrin
110 Picrotoxin
111 Fipronil
112 Lindane
113 RDX
114 T-butyl bicyclophosphorothionate
115 Dieldrin
116 Alpha,Beta-Thujone
117 Chlorpromazine
118 Verapamil
119 Immepip
120 Alpha-endosulfan
121 D-limonene
122 1,4-dichlorobenzene
123 Tylenol
124 Colchicine
125 Podofilox
126 518-2-5
127 Nocodazole
128 Benomyl
129 Carbendazim
130 Thiabendazole
131 Vincristine
132 Hydrocarbons, various
133 Phenobarbital
134 Dichloroacetic Acid
135 Cyp2f2 substrates
136 Vinclozalin
137 Flutamide
138 Bromocriptine
139 Propylene oxide
140 Nitisinone
141 Tembotrione
142 Chloroform
143 Androstenedione
144 Thiamethoxam
145 Finasteride
146 SACCHARIN, CALCIUM SALT
147 Dibenzo-p-dioxin
148 Polychlorinated biphenyl
149 Polychlorinated dibenzofurans
150 Hexachlorobenzene
151 GW6471
152 Penicillin
153 Vinyl acetate
154 Ethyl acetate
155 Propyl Acetate
156 Aspartame
157 Gabapentin
158 Indole
159 dibenzofuran
160 Halogenated phenols
161 Levothyroxine
162 1,2,4-triazole
163 Tacrolimus
164 Tebufenozide
165 Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
166 Benzoic acid, 4-chloro-, 2-benzoyl-2-(1,1-dimethylethyl)hydrazide
167 1',2'-dihydrorotenone
168 2-Imidazolidinimine, 1-[(6-chloro-3-pyridinyl)methyl]-N-nitro-, (2E)-
169 Sunitinib malate Sunitinib (INN)
170 thiazopyr
171 Pyrethrins and Pyrethroids
172 Tamoxifen
173 Raloxifene
174 Fulvestrant
175 PERFLUOROOCTANOIC ACID
176 Diethylstilbestrol
177 atrazine
178 Haloperidol
179 Reserpine
180 2,4-Dinitrophenol
181 Ketoprofen
182 Phenylbutazone
183 Amlexanox
184 Oxaprozin
185 Nitazoxanide
186 Ketorolac Tromethamine
187 Telmisartan
188 Diflunisal
189 Mefenamic acid
190 flunixin meglumine
191 Clofibrate
192 Meloxicam
193 nimesulide
194 Carprofen
195 Warfarin
196 coumachlor
197 coumatetralyl
198 chlorophacinone
199 diphacinone
200 pindone
201 3-[3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2-benzopyrone
202 Fluoxetine
203 Fluvoxamine
204 Tetrahydrocannabinol
205 pirinixic acid
206 Nafenopin
207 ciprofibrate
208 Gemfibrozil
209 trichloroacetic acid
210 Bezafibrate
211 Fenofibrate
212 iopanoic acid
213 fenoxycarb
214 DIOFENOLAN
215 pyriproxyfen
216 (7S)-Hydroprene
217 kinoprene
218 metofluthrin
219 Econazole
220 5-(N,N-hexamethylene) amiloride (HMA)
221 Small molecules: ITB3, ITB4, ITB5, ITB9
222 MPP+
223 Etoposide
224 nanoparticles
225 ROS
226 o-methyl-serine dodecylamide hydrochloride (MSDH)
227 alpha-tocopheryl succinate
228 3-aminopropanal
229 artesunate
230 naphtharazine
231 Fluoroquinolones:
232 Iron compounds
233 sertraline
234 norfluoxetine
235 Dibenzo[B,F][1,4]Oxazepine
236 2-Chlorobenzalmalononitrile
237 Nitrotoluenes (hypothesized binding)
238 Methoxyfenozide
239 Halofenozide
240 Chemical
241 20-hydroxyecdysone
242 Ponasterone A
243 Chromafenozide
244 Cyasterone
245 Makisterone A
246 Inokosterone
247 Ecdysone
248 RH-5849
249 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
250 Polycyclic aromatic hydrocarbons (PAHs)
251 TCPOBOP
252 Silver nanoparticles
253 UV-activated Titanium dioxide nanoparticles
254 Silica nanoparticles
255 Graphene oxide nanoparticles
256 Polychlorinated dibenzodioxins
257 Polybrominated diphenyl ethers
258 Isoflavones
259 Perflourinated chemicals
260 Phthalates
261 Tetrabromobisphenol A
262 Clonixin
263 Meclofenamic acid
264 2,6-dinitro-p-cresol
265 Triclopyr
266 B2,4,2',
267 5alpha-Dihydrotestosterone
268 n/a
269 Iodine deficiency
270 SSRI (Selective serotonin reuptake inhibitor)
271 Mental stress
272 Increase cortisone levels (induced by stress)
273 Gamma radiation
274 Ultraviolet B radiation
275 NonSteroidal Anti-Inflammatory Drugs (NSAID)
276 Helicobacter pylori
277 3,3'
278 3,3
279 Bioflavonoids
280 Chlorpyrifos
281 etoposide quinone
282 Ketoconazole
283 Stressor:159 dibenzofuran
284 Aristolochic acid
285 Doxorubicin
286 Tebuconazole
287 Propiconazole
288 Tioconazole
289 Miconazole
290 Fluconazole
291 Voriconazole
292 Clotrimazole
293 Tacrorimus
294 Cyclosporin
295 serotonin transporter activation
296 >85 known Cyp2E1 substrates
297 NSAID (Nonsteroidal anti-inflammatory drug) inhibits PTGS1
298 NSAID (Nonsteroidal anti-inflammatory drug) inhibits PTGS2
299 Helicobacter pylori infection
300 PPARalpha antagonists
301 NFE2/Nrf2 repression
302 EGFR ligand
303 Reactive oxygen species
304 Tributyltin
305 Single walled carbon nanotubes
306 Multi-walled carbon nanotubes
307 Sodium metam
308 Dimethyl dithiocarbamate
309 Thiram
310 Disulfiram
311 Ferbam
312 Dazornet
313 Pyrolidine dithiocarbamate
314 Mancozeb
315 Nabam-sodium
316 Ziram
317 Zineb
318 Carbon nanotubes
319 Acrolein
321 3,5-Dichlorophenol
322 Tenofovir
323 Tenofovir disoproxil fumarate
324 Adefovir
325 Adefovir dipivoxil
326 Cidofovir
327 Aminoglycosides
328 Gentamicin
329 Tobramycin
330 Vancomycin
331 Polymyxin B
332 Colistin
333 Albumin
334 low molecular weight proteins
335 Cadmium
336 Acrylamide
337 Bleomycin
338 Carbon nanotubes, Multi-walled carbon nanotubes, single-walled carbon nanotubes, carbon nanofibres
339 Carbon nanotubes, Multi-walled carbon nanotubes, Single-walled carbon nanotubes, carbon fibres
340 Methoxyacetic acid
341 Butyrate
342 Trichostatin A
343 thiomersal
344 Heptachlor
345 Endosulfan
346 Stressor:147 Dibenzo-p-dioxin
347 Polycyclic aromatic hydrocarbons
348 2,4-Dithiobiuret
349 dioxin
350 Enflurane
351 Halothane
352 Isoflurane
353 Methoxyflurane
354 Sevoflurane
355 Chemical:584015 (1-~13~C)Aniline
356 Chlorzoxazone
357 Titanium oxide (TiO)
358 Isoniazid
359 Methylcarbino
360 Ethanol
361 2,5-Hexanedione
362 Styrene
363 4-Hydroxy Nonenal
364 Acrylonitrile
365 Nitrogen mustard
366 Acetyldehyde
367 Diuron
368 Nikkomycins
369 Polyoxin B
370 Teflubenzuron
371 Diflubenzuron
372 10238-21-8
373 Glibenclamide
374 LPS
375 Stressor:338 Carbon nanotubes, Multi-walled carbon nanotubes, single-walled carbon nanotubes, carbon nanofibres
376 Lipopolysaccharride
377 Insoluble nano-sized particles
378 Virus
379 Tris(1,3-dichloropropyl)phosphate - TDCPP
380 Calcium channel blockers
381 Mercury chloride
382 Nifedipine
383 Amlodipine
384 Felodipine
385 Nisoldipine
386 Nimodipine
387 Nitrendipine
388 Diltiazem
389 Chloroquine bis(phosphate)
390 Norfloxacin
391 Ciprofloxacin
392 Rotenone, Paraquat, Piercidin A
393 • Nefazodone, Amiodarone, Flutamide, Benzbromarone, Metformin, Tolcapone, Entacapone, Diclofenac
394 Nefazodone, Amiodarone, Flutamide, Benzbromarone, Metformin, Tolcapone, Entacapone, Diclofenac
395 Antimycin A
396 Amiodarone, Benzbromarone
397 KCN
398 Nefazodone, Amiodarone, Benzbromarone, Metformin, Entacapone
399 Oligomycin A, Aurovertin
400 Nefazodone, Amiodarone, Metformin, Diclofenac
401 Valproic acid
402 Suberoylanilide hydroxamic acid
403 MS-275
404 Apicidin
405 p,p'-DDT
406 CITCO
407 Epidermal growth factor
408 Epothilone A
409 Epothilone B
410 Paclitaxel
411 Zampanolide
412 Discodermolide
413 2,3-Pentanedione
414 2,3-Butanedione
415 Light (290-700 nm)
416 Tunicamycin
417 Amphomycin
418 Fenpyroximate
419 Pyridaben
420 Benzbromarone
421 Nefazodone
422 Metformin
423 Entacapone
424 Oligomycin
425 Aurovertin
426 SC-839
427 Beta-carboline
428 BMS 345541
429 Parthenolide
430 Arsenite
431 Sulindac
432 Aspirin
433 Phenethyl isothiocyanate
434 Sulforaphane
435 Dexamethosone, IL-1 receptor antagonist（IL-1Ra）(Anakinra), anti-IL-1b antibod (Canakinumab), soluble IL-1R (Rilonacept).
436 None
437 Dexamethosone, IL-1 receptor antagonist（IL-1Ra）(Anakinra), anti-IL-1b antibod (Canakinumab), soluble IL-1R (Rilonacept).
438 IL-1 receptor antagonist（IL-1Ra）(Anakinra), anti-IL-1b antibody (Canakinumab), soluble IL-1R (Rilonacept)
439 Chemical:20384 Dexamethasone, minocycline, innamicaldehyde
440 Photoreactive chemicals
441 finasteride, dutasteride, epristeride
442 5-Azacytidine
443 Decitabine
444 Sinefungin
445 Psammaplin A
446 Hydralazine hydrochloride
447 Zebularine
448 RG 108
449 Temozolomide
450 1-phenyl 2-thiourea
451 Ionizing Radiation
452 Estrogen
453 Other DNA damaging agents
454 Hydrogen peroxide
455 Potassium bromate
456 Cadmium chloride
457 tert-Butyl hydroperoxide
458 Sodium arsenite
459 Topoisomerase inhibitors
460 Radiomimetic compounds
461 Disulphiram
462 Diethylaminobenzaldehyde
463 Citral
464 Paclobutrazol
465 nitrofen
466 4-biphenyl carboxylic acid
467 Bisdiamine
468 SB-210661
469 Vinblastine sulfate
470 Wnt
471 WNT2
472 WNT5A
473 CHIR99021
474 BIO (6-bromoindirubin-3’-oxime)
475 Kenpaullone
476 SB216763
477 TWS119
478 CHIR98014
479 Wnt ligand
480 CHIR-99021
481 CHIR-98014
482 GOLPH3
483 LiCl
484 D-2-hydroxyglutarate
485 Dexamethosone
486 minocycline
487 Pralnacasan (VX-740) and Belnacasan (VX-765)
488 cinnamic aldehyde
489 IL-1 receptor antagonist（IL-1Ra）(Anakinra)
490 anti-IL-1b antibody (Canakinumab)
491 soluble IL-1R (Rilonacept)
492 Dexamethasone
493 Aminooxyacetic acid
494 S-(4-Carboxybutyl)-D,L-homocysteine; 5-(3-Amino-3-carboxypropyl)sulfanyl-pentanoic acid
495 Stressor:488 cinnamic aldehyde
496 Stressor:491 soluble IL-1R (Rilonacept)
497 Stressor:492 Dexamethasone
498 Sunlight (wavelength: 290-700 nm)
499 Photoactivated chemicals
500 High aspect ratio material
501 acrylamio
502 Low LET Radiation
503 High LET Ra
504 High LET Radiation
505 Progesterone,estrogen,melatonin,Letrozole
506 glucocorticoids
507 Cetrorelix
508 Interleukin-6
509 benzo[a]pyrene
510 colchemid
511 Colcemid
512 2-Methoxyestradiol
513 Podophyllotoxin
514 Hydroquinone
515 4-Nitroquinoline 1-oxide
516 oxidative stress
517 Gevokizumab
518 anti-IL-1b antibody (Gevokizumab)
519 Imiquimod
520 Resiquimod
521 Bisphenol A
522 Porcupine
523 Wntless
524 testJF
525 testJF2
526 SARS-CoV
527 COVID-19
528 PM 2.5
529 Pimecrolimus
530 Gossypol
531 Kaempferol
532 Dodecylbenzene sulfonate
533 Dibefurin
534 Ascomycin
535 1,5-dibenzoyloxymethyl-norcantharidin
536 Azathioprine
537 Methotrexate
538 Benzo(a)pyrene
539 Urethane
540 1,2:5,6-dibenzanthracene
541 psychosocial stress
542 Radiation
543 beta-Sitosterol
544 Abamectin
545 Carbenoxolone
546 Malathion
547 Dimethoate
548 Triphenyl phosphate
549 Atorvastatin
550 Streptozocin
551 Losartan
552 furan
553 acetone
554 too many stressors to list
555 Simvastatin
556 Vinclozolin
557 Triticonazole
558 Flusilazole
559 Epoxiconazole
560 Cyproterone acetate
561 Butylparaben
562 p,p'-DDE
563 Fenitrothion
564 Linuron
565 Procymidone
566 di-n-hexyl phthalate
567 Dicyclohexyl phthalate
568 butyl benzyl phthalate
569 monobenzyl phthalate
570 di-n-heptyl phthalate
571 ferric nitrilotriacetate
572 N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide
573 Beclomethasone dipropionate monohydrate
574 Metyrapone
575 Lysodren, Mitotan, Mitotane
576 Etomidate
577 Osilodrostat(LCI699)
578 Glycyrrhizin
579 PF915275
580 Bicalutamide
581 Stressor:286 Tebuconazole
582 Propylpyrazoletriol
583 4-Hydroxytamoxifen
584 Stressor:48 Propylthiouracil
585 PF-06651600 (CAS No：1792180-81-4),
586 RB1
587 PF-06651600 (CAS No：1792180-81-4), RB1
588 Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide Pimozide
589 Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide
590 Tofacitinib (CP690,550)
591 Cyclosporin, FK506, Basiliximab, PFOA (perfluorooctanoic acid)
593 Polyoxin D
594 Captafol
595 Captan
596 Folpet
597 Capta
598 Exemestane
599 Stressor:292 Clotrimazole
600 Pentachlorophenol
601 Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
602 Carbonyl cyanide m-chlorophenyl hydrazone
603 Triclosan
604 Dinoseb
605 Emodin
606 Malonoben
607 Stressor:205 pirinixic acid (WY-14,643)
608 Pralnacasan (VX-740)
609 Belnacasan (VX-765)
610 HMR3480
611 Pralnacasan (VX-740, HMR3480)
612 curcumin
613 inguratimod
614 iguratimod
615 epigallocathechin gallate
616 TAK-242
617 IRAK4 inhibitors
618 Wy-14,6423
619 SARS-CoV and CoV-NL63, SARS-CoV
620 HCoV-NL63
621 DX600
622 cationic polyamidoamine dendrimer (nanoparticle)
623 Hy
624 Sars-CoV-2
625 bacteria
626 fungi
627 Dummy Stressor