Prototypical Stressors

ID Prototypical Stressor Name Associated Chemical(s): Name, CAS-RN, DTXSID Associated AOPs
2 (2-ethylhexyl) hydrogen phthalate
  • MEHP, CAS-RN: 4376-20-9, DTXSID2025680
3 1-Methylsulfonyloxyethane
  • Ethyl methanesulfonate, CAS-RN: 62-50-0, DTXSID6025309
4 17beta-Estradiol
  • 17beta-Estradiol, CAS-RN: 50-28-2, DTXSID0020573
314
5 17beta-Trenbolone
  • 17beta-Trenbolone, CAS-RN: 10161-33-8, DTXSID0034192
23, 376
6 2(3H)-Benzothiazolethione
7 2-mercaptobenzothiazole
  • 2-Mercaptobenzothiazole, CAS-RN: 149-30-4, DTXSID1020807
8 Aceytlsalicylic acid
  • Aspirin, CAS-RN: 50-78-2, DTXSID5020108
9 Allyl Alcohol
  • Allyl alcohol, CAS-RN: 107-18-6, DTXSID8020044
38
10 Benzo(k)fluoranthene
  • Benzo(k)fluoranthene, CAS-RN: 207-08-9, DTXSID0023909
11 Bis(2-ethylhexyl) phthalate
  • Di(2-ethylhexyl) phthalate, CAS-RN: 117-81-7, DTXSID5020607
37, 307
12 Butyl 4-hydroxybenzoate
  • Butylparaben, CAS-RN: 94-26-8, DTXSID3020209
13 Carbon tetrachloride
  • Carbon tetrachloride, CAS-RN: 56-23-5, DTXSID8020250
38
14 Dibutyl phthalate
  • Dibutyl phthalate, CAS-RN: 84-74-2, DTXSID2021781
307
15 Diclofenac sodium
  • Diclofenac sodium, CAS-RN: 15307-79-6, DTXSID3037208
177, 186
16 Diethyl nitrosamine
  • N-Nitrosodiethylamine, CAS-RN: 55-18-5, DTXSID2021028
17 Diethyl sulfate
  • Diethyl sulfate, CAS-RN: 64-67-5, DTXSID1024045
18 Dimethyl nitrosamine
  • N-Nitrosodimethylamine, CAS-RN: 62-75-9, DTXSID7021029
38
19 Dimethyl sulfate
  • Dimethyl sulfate, CAS-RN: 77-78-1, DTXSID5024055
20 Dioxin and dioxin-like compounds
  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin, CAS-RN: 1746-01-6, DTXSID2021315
  • Acetamide, CAS-RN: 60-35-5, DTXSID7020005
21 Domoic acid
  • L-Domoic acid, CAS-RN: 14277-97-5, DTXSID20274180
22 Ethyl methanesulfonate
  • Ethyl methanesulfonate, CAS-RN: 62-50-0, DTXSID6025309
23 Ethyl nitrosourea
  • 1-Ethyl-1-nitrosourea, CAS-RN: 759-73-9, DTXSID8020593
24 Ethyl-N'-nitro-N-nitrosoguanidine
  • N-Ethyl-N'-nitro-N-nitrosoguanidine, CAS-RN: 63885-23-4, DTXSID3020592
25 Ethylene thiourea
  • Ethylene thiourea, CAS-RN: 96-45-7, DTXSID5020601
271
26 Fadrozole
  • Fadrozole, CAS-RN: 102676-47-1, DTXSID5034141
153, 346
27 Indomethacin
  • Indomethacin, CAS-RN: 53-86-1, DTXSID9020740
177
28 Isopropyl methanesulfonate
  • Isopropyl methanesulfonate, CAS-RN: 926-06-7, DTXSID8031497
29 Kainic acid
  • Kainic acid, CAS-RN: 487-79-6, DTXSID7040526
30 Lead(II)
31 Lead(II) acetate trihydrate
  • Lead(II) acetate trihydrate, CAS-RN: 6080-56-4, DTXSID3031521
32 Letrozole
  • Letrozole, CAS-RN: 112809-51-5, DTXSID4023202
  • Fadrozole, CAS-RN: 102676-47-1, DTXSID5034141
153, 346
33 Maneb
  • Maneb, CAS-RN: 12427-38-2, DTXSID9020794
242
34 Mercaptobenzothiazole
  • 2-Mercaptobenzothiazole, CAS-RN: 149-30-4, DTXSID1020807
175, 159
35 Mercuric chloride
  • Mercuric chloride, CAS-RN: 7487-94-7, DTXSID5020811
17
36 Mercury
  • Mercury, CAS-RN: 7439-97-6, DTXSID1024172
37 Methimazole
  • Methimazole, CAS-RN: 60-56-0, DTXSID4020820
175, 159, 42, 271, 363
38 Methyl methanesulfonate
  • Methyl methanesulfonate, CAS-RN: 66-27-3, DTXSID7020845
39 Methyl-l-N'-nitro-N-nitroguanidine
  • N-Methyl-N'-nitro-N-nitrosoguanidine, CAS-RN: 70-25-7, DTXSID2020846
40 Methylmercuric(II) chloride
  • Methylmercuric(II) chloride, CAS-RN: 115-09-3, DTXSID5020813
17
41 Naproxen
  • Naproxen, CAS-RN: 22204-53-1, DTXSID4040686
42 Ochratoxin A
  • Ochratoxin A, CAS-RN: 303-47-9, DTXSID7021073
43 Organophosphates
  • Parathion, CAS-RN: 56-38-2, DTXSID7021100
  • Pinacolyl methylphosphonofluoridate, CAS-RN: 96-64-0, DTXSID2031906
405, 450
44 Paraquat
  • Paraquat, CAS-RN: 4685-14-7, DTXSID3034799
45 Parathion
  • Parathion, CAS-RN: 56-38-2, DTXSID7021100
46 Phenanthrene
  • Phenanthrene, CAS-RN: 85-01-8, DTXSID6024254
47 Prochloraz
  • Prochloraz, CAS-RN: 67747-09-5, DTXSID4024270
346
48 Propylthiouracil
  • 6-Propyl-2-thiouracil, CAS-RN: 51-52-5, DTXSID5021209
175, 159, 42, 271, 363
49 Resorcinol
  • Resorcinol, CAS-RN: 108-46-3, DTXSID2021238
  • Resorcinol bis(diphenyl phosphate), CAS-RN: 57583-54-7, DTXSID8069197
50 Rotenone
  • Rotenone, CAS-RN: 83-79-4, DTXSID6021248
3
51 Selected AHR Ligands
52 Spironolactone
  • Spironolactone, CAS-RN: 52-01-7, DTXSID6034186
53 Thiouracil
  • Thiouracil, CAS-RN: 141-90-2, DTXSID4021347
54 Trimethyltin chloride
  • Trimethyltin chloride, CAS-RN: 1066-45-1, DTXSID6042496
55 Vatalanib
  • Vatalanib, CAS-RN: 212141-54-3, DTXSID2046919
  • Sunitinib malate, CAS-RN: 341031-54-7, DTXSID4046492
43
56 Ethylenethiourea
  • Ethylene thiourea, CAS-RN: 96-45-7, DTXSID5020601
57 Acetaminophen
  • Acetamide, CAS-RN: 60-35-5, DTXSID7020005
  • Acetaminophen, CAS-RN: 103-90-2, DTXSID2020006
  • Acetohexamide, CAS-RN: 968-81-0, DTXSID7020007
260
58 Mercaptobenzole
59 Lead
  • Lead, CAS-RN: 7439-92-1, DTXSID2024161
12
60 Retinol
  • Retinol, CAS-RN: 68-26-8, DTXSID3023556
38
61 Aflatoxin B1
  • Aflatoxin B1, CAS-RN: 1162-65-8, DTXSID9020035
397
62 Benzidine
  • Benzidine, CAS-RN: 92-87-5, DTXSID2020137
63 Thioacetamide
  • Thioacetamide, CAS-RN: 62-55-5, DTXSID9021340
38
64 Mono(2-ethylhexyl) phthalate
65 Di(2-ethylhexyl) phthalate
  • Di(2-ethylhexyl) phthalate, CAS-RN: 117-81-7, DTXSID5020607
66 Perchlorate
  • Perchlorate, CAS-RN: 14797-73-0, DTXSID6024252
176, 54
67 Nitrate
  • Nitrate, CAS-RN: 14797-55-8, DTXSID5024217
54
68 Thiocyanate
  • Thiocyanate, CAS-RN: 302-04-5, DTXSID8047763
54
69 Dysidenin
54
70 Troglitazone
  • Troglitazone, CAS-RN: 97322-87-7, DTXSID8023719
163
71 1-CHLORO-2,4- DINITROBENZENE
  • Glutathione, CAS-RN: 70-18-8, DTXSID6023101
72 Amitrole
  • Amitrole, CAS-RN: 61-82-5, DTXSID0020076
73 131-55-5
74 2,2',4,4'-Tetrahydroxybenzophenone
  • 2,2',4,4'-Tetrahydroxybenzophenone, CAS-RN: 131-55-5, DTXSID5041306
175, 152
75 Daidzein
  • Daidzein, CAS-RN: 486-66-8, DTXSID9022310
76 Genistein
  • Genistein, CAS-RN: 446-72-0, DTXSID5022308
167
77 4-Nonylphenol
  • 4-Nonylphenol, CAS-RN: 104-40-5, DTXSID5033836
78 4-propoxyphenol
79 Sulfamethazine
  • Sulfamethazine, CAS-RN: 57-68-1, DTXSID6021290
80 N-methyl Carbamates
405
81 Aryltrifluoroborates
54
82 Ibuprofen
  • Ibuprofen, CAS-RN: 15687-27-1, DTXSID5020732
177
83 Emamectin benzoate
  • Emamectin benzoate, CAS-RN: 155569-91-8, DTXSID0034566
161, 160
84 1-Chloro-4-nitrobenzene
  • 1-Chloro-4-nitrobenzene, CAS-RN: 100-00-5, DTXSID5020281
85 169590-42-5
86 Celecoxib
  • Celecoxib, CAS-RN: 169590-42-5, DTXSID0022777
177
87 3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]-1H-pyrazole
88 Tetraconazole
  • Tetraconazole, CAS-RN: 112281-77-3, DTXSID8034956
89 2058-46-0
90 Oxytetracycline hydrochloride
  • Oxytetracycline hydrochloride, CAS-RN: 2058-46-0, DTXSID5021097
91 Sodium (4-fluoro-2-{[(1S)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide
92 Carbamazepine
  • Carbamazepine, CAS-RN: 298-46-4, DTXSID4022731
93 Topiramate
  • Topiramate, CAS-RN: 97240-79-4, DTXSID8023688
94 Tetrodotoxin
95 Amiodarone
  • Amiodarone, CAS-RN: 1951-25-3, DTXSID7022592
96 Phenytoin
97 Valproate
212
98 Zonisamide
  • Zonisamide, CAS-RN: 68291-97-4, DTXSID9046023
99 Lidocaine
  • Lidocaine, CAS-RN: 137-58-6, DTXSID1045166
100 2,4-dinitrotoluene
  • 2,4-Dinitrotoluene, CAS-RN: 121-14-2, DTXSID0020529
101 2,6-dinitrotoluene
  • 2,6-Dinitrotoluene, CAS-RN: 606-20-2, DTXSID5020528
102 2-amino-4,6-dinitrotoluene
  • 2-Amino-4,6-dinitrotoluene, CAS-RN: 35572-78-2, DTXSID6044068
103 Cypermethrin
  • Cypermethrin, CAS-RN: 52315-07-8, DTXSID1023998
104 Permethrin
  • Permethrin, CAS-RN: 52645-53-1, DTXSID8022292
105 Esfenvalerate
  • Esfenvalerate, CAS-RN: 66230-04-4, DTXSID4032667
106 Tralomethrin
  • Tralomethrin, CAS-RN: 66841-25-6, DTXSID0024343
107 Bifenthrin
  • Bifenthrin, CAS-RN: 82657-04-3, DTXSID9020160
108 Cyfluthrin
  • Cyfluthrin, CAS-RN: 68359-37-5, DTXSID5035957
109 Lambda-Cyhalothrin
  • lambda-Cyhalothrin, CAS-RN: 91465-08-6, DTXSID7032559
110 Picrotoxin
  • Picrotoxin, CAS-RN: 124-87-8, DTXSID7045605
10
111 Fipronil
  • Fipronil, CAS-RN: 120068-37-3, DTXSID4034609
10
112 Lindane
  • Lindane, CAS-RN: 58-89-9, DTXSID2020686
10
113 RDX
10
114 T-butyl bicyclophosphorothionate
115 Dieldrin
  • Dieldrin, CAS-RN: 60-57-1, DTXSID9020453
10
116 Alpha,Beta-Thujone
117 Chlorpromazine
  • Chlorpromazine, CAS-RN: 50-53-3, DTXSID0022808
118 Verapamil
  • Verapamil, CAS-RN: 52-53-9, DTXSID9041152
261
119 Immepip
120 Alpha-endosulfan
121 D-limonene
  • D-Limonene, CAS-RN: 5989-27-5, DTXSID1020778
122 1,4-dichlorobenzene
  • 1,4-Dichlorobenzene, CAS-RN: 106-46-7, DTXSID1020431
123 Tylenol
124 Colchicine
  • Colchicine, CAS-RN: 64-86-8, DTXSID5024845
106
125 Podofilox
  • Podofilox, CAS-RN: 518-28-5, DTXSID3045645
126 518-2-5
127 Nocodazole
  • Nocodazole, CAS-RN: 31430-18-9, DTXSID9031800
106
128 Benomyl
  • Benomyl, CAS-RN: 17804-35-2, DTXSID5023900
106
129 Carbendazim
  • Carbendazim, CAS-RN: 10605-21-7, DTXSID4024729
130 Thiabendazole
  • Thiabendazole, CAS-RN: 148-79-8, DTXSID0021337
131 Vincristine
  • Vincristine, CAS-RN: 57-22-7, DTXSID1032278
132 Hydrocarbons, various
133 Phenobarbital
  • Phenobarbital, CAS-RN: 50-06-6, DTXSID5021122
162, 107
134 Dichloroacetic Acid
  • Dichloroacetic acid, CAS-RN: 79-43-6, DTXSID2020428
135 Cyp2f2 substrates
136 Vinclozalin
137 Flutamide
  • Flutamide, CAS-RN: 13311-84-7, DTXSID7032004
306, 345
138 Bromocriptine
  • Bromocriptine, CAS-RN: 25614-03-3, DTXSID1022687
139 Propylene oxide
140 Nitisinone
141 Tembotrione
  • Tembotrione, CAS-RN: 335104-84-2, DTXSID5047037
142 Chloroform
  • Chloroform, CAS-RN: 67-66-3, DTXSID1020306
143 Androstenedione
144 Thiamethoxam
  • Thiamethoxam, CAS-RN: 153719-23-4, DTXSID2034962
145 Finasteride
305, 306
146 SACCHARIN, CALCIUM SALT
147 Dibenzo-p-dioxin
  • Dibenzo-p-dioxin, CAS-RN: 262-12-4, DTXSID8020410
131
148 Polychlorinated biphenyl
150, 152, 131
149 Polychlorinated dibenzofurans
150
150 Hexachlorobenzene
  • Hexachlorobenzene, CAS-RN: 118-74-1, DTXSID2020682
131
151 GW6471
6
152 Penicillin
153 Vinyl acetate
  • Vinyl acetate, CAS-RN: 108-05-4, DTXSID3021431
136
154 Ethyl acetate
  • Ethyl acetate, CAS-RN: 141-78-6, DTXSID1022001
155 Propyl Acetate
  • Propyl acetate, CAS-RN: 109-60-4, DTXSID6021901
156 Aspartame
  • Aspartame, CAS-RN: 22839-47-0, DTXSID0020107
157 Gabapentin
  • Gabapentin, CAS-RN: 60142-96-3, DTXSID0020074
158 Indole
  • Indole, CAS-RN: 120-72-9, DTXSID0020737
159 dibenzofuran
  • Dibenzofuran, CAS-RN: 132-64-9, DTXSID2021993
160 Halogenated phenols
152
161 Levothyroxine
  • Levothyroxine, CAS-RN: 51-48-9, DTXSID8023214
162 1,2,4-triazole
153
163 Tacrolimus (also FK506)
  • Tacrolimus, CAS-RN: 104987-11-3, DTXSID5046354
154
164 Tebufenozide
  • Tebufenozide, CAS-RN: 112410-23-8, DTXSID4034948
4
165 Benzoic acid, 3-methoxy-2-methyl-, 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide
166 Benzoic acid, 4-chloro-, 2-benzoyl-2-(1,1-dimethylethyl)hydrazide
167 1',2'-dihydrorotenone
  • 1',2'-Dihydrorotenone, CAS-RN: 6659-45-6, DTXSID5041227
168 2-Imidazolidinimine, 1-[(6-chloro-3-pyridinyl)methyl]-N-nitro-, (2E)-
169 Sunitinib malate Sunitinib (INN)
43
170 thiazopyr
  • Thiazopyr, CAS-RN: 117718-60-2, DTXSID1032488
162
171 Pyrethrins and Pyrethroids
162, 442
172 Tamoxifen
  • Tamoxifen, CAS-RN: 10540-29-1, DTXSID1034187
165, 440
173 Raloxifene
  • Raloxifene, CAS-RN: 84449-90-1, DTXSID3023550
165, 440
174 Fulvestrant
  • Fulvestrant, CAS-RN: 129453-61-8, DTXSID4022369
165
175 PERFLUOROOCTANOIC ACID
166, 37
176 Diethylstilbestrol
  • Diethylstilbestrol, CAS-RN: 56-53-1, DTXSID3020465
167
177 atrazine
  • Atrazine, CAS-RN: 1912-24-9, DTXSID9020112
168, 169
178 Haloperidol
  • Haloperidol, CAS-RN: 52-86-8, DTXSID4034150
170
179 Reserpine
  • Reserpine, CAS-RN: 50-55-5, DTXSID7021237
170
180 2,4-Dinitrophenol
  • 2,4-Dinitrophenol, CAS-RN: 51-28-5, DTXSID0020523
263
181 Ketoprofen
  • Ketoprofen, CAS-RN: 22071-15-4, DTXSID6020771
177
182 Phenylbutazone
  • Phenylbutazone, CAS-RN: 50-33-9, DTXSID9021136
177
183 Amlexanox
184 Oxaprozin
  • Oxaprozin, CAS-RN: 21256-18-8, DTXSID1045118
185 Nitazoxanide
  • Nitazoxanide, CAS-RN: 55981-09-4, DTXSID5033757
186 Ketorolac Tromethamine
  • Ketorolac tromethamine, CAS-RN: 74103-07-4, DTXSID0045597
187 Telmisartan
  • Telmisartan, CAS-RN: 144701-48-4, DTXSID8023636
188 Diflunisal
  • Diflunisal, CAS-RN: 22494-42-4, DTXSID5022932
189 Mefenamic acid
  • Mefenamic acid, CAS-RN: 61-68-7, DTXSID5023243
190 flunixin meglumine
  • Flunixin meglumine, CAS-RN: 42461-84-7, DTXSID1045584
177
191 Clofibrate
  • Clofibrate, CAS-RN: 637-07-0, DTXSID3020336
177, 37
192 Meloxicam
  • Meloxicam, CAS-RN: 71125-38-7, DTXSID1020803
177
193 nimesulide
  • Nimesulide, CAS-RN: 51803-78-2, DTXSID3037250
177
194 Carprofen
  • Carprofen, CAS-RN: 53716-49-7, DTXSID1045871
177
195 Warfarin
  • Warfarin, CAS-RN: 81-81-2, DTXSID5023742
187
196 coumachlor
  • Coumachlor, CAS-RN: 81-82-3, DTXSID8041797
187
197 coumatetralyl
  • Coumatetralyl, CAS-RN: 5836-29-3, DTXSID8041799
187
198 chlorophacinone
  • Chlorophacinone, CAS-RN: 3691-35-8, DTXSID2032348
187
199 diphacinone
  • Diphacinone, CAS-RN: 82-66-6, DTXSID4032378
187
200 pindone
  • Pindone, CAS-RN: 83-26-1, DTXSID1025930
187
201 3-[3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2-benzopyrone
187
202 Fluoxetine
195, 97, 203
203 Fluvoxamine
  • Fluvoxamine, CAS-RN: 54739-18-3, DTXSID2044002
195, 203
204 Tetrahydrocannabinol
  • Tetrahydrocannabinol, CAS-RN: 1972-08-3, DTXSID6021327
205 pirinixic acid
  • Pirinixic acid, CAS-RN: 50892-23-4, DTXSID4020290
37
206 Nafenopin
  • Nafenopin, CAS-RN: 3771-19-5, DTXSID8020911
37
207 ciprofibrate
  • Ciprofibrate, CAS-RN: 52214-84-3, DTXSID8020331
37
208 Gemfibrozil
  • Gemfibrozil, CAS-RN: 25812-30-0, DTXSID0020652
37
209 trichloroacetic acid
  • Trichloroacetic acid, CAS-RN: 76-03-9, DTXSID1021378
210 Bezafibrate
  • Bezafibrate, CAS-RN: 41859-67-0, DTXSID3029869
37
211 Fenofibrate
  • Fenofibrate, CAS-RN: 49562-28-9, DTXSID2029874
37
212 iopanoic acid
  • Iopanoic acid, CAS-RN: 96-83-3, DTXSID6023159
155
213 fenoxycarb
  • Fenoxycarb, CAS-RN: 72490-01-8, DTXSID7032393
201
214 DIOFENOLAN
  • Diofenolan, CAS-RN: 63837-33-2, DTXSID2041884
201
215 pyriproxyfen
  • Pyriproxyfen, CAS-RN: 95737-68-1, DTXSID1032640
201
216 (7S)-Hydroprene
  • (7S)-Hydroprene, CAS-RN: 65733-18-8, DTXSID6035784
201
217 kinoprene
  • Kinoprene, CAS-RN: 42588-37-4, DTXSID3032624
201
218 metofluthrin
  • Metofluthrin, CAS-RN: 240494-70-6, DTXSID4034738
107
219 Econazole
220 5-(N,N-hexamethylene) amiloride (HMA)
221 Small molecules: ITB3, ITB4, ITB5, ITB9
222 MPP+
3
223 Etoposide
  • Etoposide, CAS-RN: 33419-42-0, DTXSID5023035
202
224 nanoparticles
144, 392, 451
225 ROS
144
226 o-methyl-serine dodecylamide hydrochloride (MSDH)
144
227 alpha-tocopheryl succinate
228 3-aminopropanal
144
229 artesunate
  • Artesunate, CAS-RN: 88495-63-0, DTXSID3042681
144
230 naphtharazine
231 Fluoroquinolones:
232 Iron compounds
233 sertraline
  • Sertraline, CAS-RN: 79617-96-2, DTXSID6023577
203
234 norfluoxetine
203
235 Dibenzo[B,F][1,4]Oxazepine
196
236 2-Chlorobenzalmalononitrile
196
237 Nitrotoluenes (hypothesized binding)
6
238 Methoxyfenozide
  • Methoxyfenozide, CAS-RN: 161050-58-4, DTXSID3032628
4
239 Halofenozide
  • Halofenozide, CAS-RN: 112226-61-6, DTXSID4032619
4
240 Chemical
205
241 20-hydroxyecdysone
  • 20-Hydroxyecdysone, CAS-RN: 5289-74-7, DTXSID5040388
4
242 Ponasterone A
  • Ponasterone A, CAS-RN: 13408-56-5, DTXSID0040595
4
243 Chromafenozide
  • Chromafenozide, CAS-RN: 143807-66-3, DTXSID4057976
4
244 Cyasterone
4
245 Makisterone A
4
246 Inokosterone
  • Inokosterone, CAS-RN: 15130-85-5, DTXSID40164756
4
247 Ecdysone
4
248 RH-5849
4
249 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
21
250 Polycyclic aromatic hydrocarbons (PAHs)
131, 397
251 TCPOBOP
107
252 Silver nanoparticles
207
253 UV-activated Titanium dioxide nanoparticles
208, 451
254 Silica nanoparticles
209
255 Graphene oxide nanoparticles
210, 237
256 Polychlorinated dibenzodioxins
152, 150
257 Polybrominated diphenyl ethers
152
258 Isoflavones
152
259 Perflourinated chemicals
152
260 Phthalates
152
261 Tetrabromobisphenol A
  • 3,3',5,5'-Tetrabromobisphenol A, CAS-RN: 79-94-7, DTXSID1026081
152
262 Clonixin
  • Clonixin, CAS-RN: 17737-65-4, DTXSID2046121
152
263 Meclofenamic acid
  • Meclofenamic acid, CAS-RN: 644-62-2, DTXSID0048559
152
264 2,6-dinitro-p-cresol
152
265 Triclopyr
  • Triclopyr, CAS-RN: 55335-06-3, DTXSID0032497
152
266 B2,4,2',
267 5alpha-Dihydrotestosterone
  • 5alpha-Dihydrotestosterone, CAS-RN: 521-18-6, DTXSID9022364
376
268 n/a
269 Iodine deficiency
270 SSRI (Selective serotonin reuptake inhibitor)
214, 226
271 Mental stress
403
272 Increase cortisone levels (induced by stress)
214, 221, 222
273 Gamma radiation
216, 238, 299, 311, 386, 387, 388, 396
274 Ultraviolet B radiation
331, 327, 328, 329, 330, 389, 388, 386, 387
275 NonSteroidal Anti-Inflammatory Drugs (NSAID)
217
276 Helicobacter pylori
217
277 3,3'
278 3,3
279 Bioflavonoids
202
280 Chlorpyrifos
  • Chlorpyrifos, CAS-RN: 2921-88-2, DTXSID4020458
202
281 etoposide quinone
202
282 Ketoconazole
  • Ketoconazole, CAS-RN: 65277-42-1, DTXSID7029879
218, 219, 349
283 Stressor:159 dibenzofuran
284 Aristolochic acid
  • Aristolochic acid, CAS-RN: 313-67-7, DTXSID0040969
397
285 Doxorubicin
  • Doxorubicin, CAS-RN: 23214-92-8, DTXSID8021480
286 Tebuconazole
  • Tebuconazole, CAS-RN: 107534-96-3, DTXSID9032113
287 Propiconazole
  • Propiconazole, CAS-RN: 60207-90-1, DTXSID8024280
288 Tioconazole
  • Tioconazole, CAS-RN: 65899-73-2, DTXSID3046619
289 Miconazole
  • Miconazole, CAS-RN: 22916-47-8, DTXSID6023319
290 Fluconazole
  • Fluconazole, CAS-RN: 86386-73-4, DTXSID3020627
291 Voriconazole
  • Voriconazole, CAS-RN: 137234-62-9, DTXSID5046485
292 Clotrimazole
  • Clotrimazole, CAS-RN: 23593-75-1, DTXSID7029871
293 Tacrorimus
294 Cyclosporin
154
295 serotonin transporter activation
223, 224, 225
296 >85 known Cyp2E1 substrates
220
297 NSAID (Nonsteroidal anti-inflammatory drug) inhibits PTGS1
227
298 NSAID (Nonsteroidal anti-inflammatory drug) inhibits PTGS2
228
299 Helicobacter pylori infection
229
300 PPARalpha antagonists
6
301 NFE2/Nrf2 repression
232
302 EGFR ligand
303 Reactive oxygen species
148, 149, 282, 296
304 Tributyltin
  • Tributyltin, CAS-RN: 688-73-3, DTXSID0040709
72
305 Single walled carbon nanotubes
306 Multi-walled carbon nanotubes
409
307 Sodium metam
242
308 Dimethyl dithiocarbamate
242
309 Thiram
  • Thiram, CAS-RN: 137-26-8, DTXSID5021332
242
310 Disulfiram
  • Disulfiram, CAS-RN: 97-77-8, DTXSID1021322
242, 436
311 Ferbam
  • Ferbam, CAS-RN: 14484-64-1, DTXSID8020624
242
312 Dazornet
242
313 Pyrolidine dithiocarbamate
242
314 Mancozeb
  • Mancozeb, CAS-RN: 8018-01-7, DTXSID0034695
242
315 Nabam-sodium
  • Nabam-sodium, CAS-RN: 142-59-6, DTXSID5020603
242
316 Ziram
  • Ziram, CAS-RN: 137-30-4, DTXSID0021464
242
317 Zineb
  • Zineb, CAS-RN: 12122-67-7, DTXSID5021465
242
318 Carbon nanotubes
241, 237
319 Acrolein
  • Acrolein, CAS-RN: 107-02-8, DTXSID5020023
411, 424
321 3,5-Dichlorophenol
  • 3,5-Dichlorophenol, CAS-RN: 591-35-5, DTXSID2025006
245, 263
322 Tenofovir
  • Tenofovir, CAS-RN: 147127-20-6, DTXSID9040132
256
323 Tenofovir disoproxil fumarate
  • Tenofovir disoproxil fumarate, CAS-RN: 202138-50-9, DTXSID5050426
256
324 Adefovir
  • Adefovir, CAS-RN: 106941-25-7, DTXSID6046214
256
325 Adefovir dipivoxil
  • Adefovir dipivoxil, CAS-RN: 142340-99-6, DTXSID5046487
256
326 Cidofovir
  • Cidofovir, CAS-RN: 113852-37-2, DTXSID3043734
256
327 Aminoglycosides
257
328 Gentamicin
  • Gentamicin, CAS-RN: 1403-66-3, DTXSID5034642
257
329 Tobramycin
  • Tobramycin, CAS-RN: 32986-56-4, DTXSID8023680
257
330 Vancomycin
  • Vancomycin, CAS-RN: 1404-90-6, DTXSID0042664
257
331 Polymyxin B
  • Polymyxin B, CAS-RN: 1404-26-8, DTXSID1048467
257
332 Colistin
  • Colistin, CAS-RN: 1066-17-7, DTXSID1040663
257
333 Albumin
  • Albumin, CAS-RN: NOCAS_40409, DTXSID1040409
257
334 low molecular weight proteins
257
335 Cadmium
  • Cadmium, CAS-RN: 7440-43-9, DTXSID1023940
257
336 Acrylamide
  • Acrylamide, CAS-RN: 79-06-1, DTXSID5020027
17
337 Bleomycin
  • Bleomycin, CAS-RN: 11056-06-7, DTXSID1030862
173
338 Carbon nanotubes, Multi-walled carbon nanotubes, single-walled carbon nanotubes, carbon nanofibres
173
339 Carbon nanotubes, Multi-walled carbon nanotubes, Single-walled carbon nanotubes, carbon fibres
340 Methoxyacetic acid
  • Methoxyacetic acid, CAS-RN: 625-45-6, DTXSID1031591
212
341 Butyrate
  • Butyrate, CAS-RN: 461-55-2, DTXSID8040432
212, 274
342 Trichostatin A
  • Trichostatin A, CAS-RN: 58880-19-6, DTXSID6037063
212, 274
343 thiomersal
344 Heptachlor
  • Heptachlor, CAS-RN: 76-44-8, DTXSID3020679
10
345 Endosulfan
  • Endosulfan, CAS-RN: 115-29-7, DTXSID1020560
10
346 Stressor:147 Dibenzo-p-dioxin
347 Polycyclic aromatic hydrocarbons
  • Polycyclic aromatic hydrocarbons, CAS-RN: NOCAS_44043, DTXSID3044043
348 2,4-Dithiobiuret
  • 2,4-Dithiobiuret, CAS-RN: 541-53-7, DTXSID2034968
349 dioxin
350 Enflurane
  • Enflurane, CAS-RN: 13838-16-9, DTXSID1020562
260
351 Halothane
  • Halothane, CAS-RN: 151-67-7, DTXSID4025371
260
352 Isoflurane
  • Isoflurane, CAS-RN: 26675-46-7, DTXSID3020752
260
353 Methoxyflurane
  • Methoxyflurane, CAS-RN: 76-38-0, DTXSID7025556
260
354 Sevoflurane
  • Sevoflurane, CAS-RN: 28523-86-6, DTXSID8046614
260
355 Chemical:584015 (1-~13~C)Aniline
260
356 Chlorzoxazone
  • Chlorzoxazone, CAS-RN: 95-25-0, DTXSID9022813
260
357 Titanium oxide (TiO)
  • Titanium oxide (TiO), CAS-RN: 12137-20-1, DTXSID7065253
260
358 Isoniazid
  • Isoniazid, CAS-RN: 54-85-3, DTXSID8020755
260
359 Methylcarbino
360 Ethanol
  • Ethanol, CAS-RN: 64-17-5, DTXSID9020584
260, 436
361 2,5-Hexanedione
  • 2,5-Hexanedione, CAS-RN: 110-13-4, DTXSID8030138
362 Styrene
  • Styrene, CAS-RN: 100-42-5, DTXSID2021284
363 4-Hydroxy Nonenal
364 Acrylonitrile
  • Acrylonitrile, CAS-RN: 107-13-1, DTXSID5020029
365 Nitrogen mustard
  • Nitrogen mustard, CAS-RN: 51-75-2, DTXSID2020975
366 Acetyldehyde
367 Diuron
  • Diuron, CAS-RN: 330-54-1, DTXSID0020446
335
368 Nikkomycins
  • Nikkomycins, CAS-RN: 59456-70-1, DTXSID5058436
342, 360
369 Polyoxin B
  • Polyoxin B, CAS-RN: 19396-06-6, DTXSID3058329
342, 360
370 Teflubenzuron
  • Teflubenzuron, CAS-RN: 83121-18-0, DTXSID6042440
343
371 Diflubenzuron
  • Diflubenzuron, CAS-RN: 35367-38-5, DTXSID1024049
343
372 10238-21-8
373 Glibenclamide
343
374 LPS
375 Stressor:338 Carbon nanotubes, Multi-walled carbon nanotubes, single-walled carbon nanotubes, carbon nanofibres
376 Lipopolysaccharride
  • Lipopolysaccharride, CAS-RN: NOCAS_36695, DTXSID4036695
237
377 Insoluble nano-sized particles
237
378 Virus
237, 374
379 Tris(1,3-dichloropropyl)phosphate - TDCPP
  • TDCPP, CAS-RN: 13674-87-8, DTXSID9026261
380 Calcium channel blockers
261
381 Mercury chloride
  • Mercury chloride, CAS-RN: 51312-24-4, DTXSID40858724
382 Nifedipine
  • Nifedipine, CAS-RN: 21829-25-4, DTXSID2025715
261
383 Amlodipine
  • Amlodipine, CAS-RN: 88150-42-9, DTXSID7022596
261
384 Felodipine
  • Felodipine, CAS-RN: 72509-76-3, DTXSID4023042
261
385 Nisoldipine
  • Nisoldipine, CAS-RN: 63675-72-9, DTXSID0023371
261
386 Nimodipine
  • Nimodipine, CAS-RN: 66085-59-4, DTXSID5023370
261
387 Nitrendipine
  • Nitrendipine, CAS-RN: 39562-70-4, DTXSID0023373
261
388 Diltiazem
  • Diltiazem, CAS-RN: 42399-41-7, DTXSID9022940
261
389 Chloroquine bis(phosphate)
  • Chloroquine bis(phosphate), CAS-RN: 50-63-5, DTXSID7044681
144
390 Norfloxacin
  • Norfloxacin, CAS-RN: 70458-96-7, DTXSID7037680
144
391 Ciprofloxacin
  • Ciprofloxacin, CAS-RN: 85721-33-1, DTXSID8022824
144
392 Rotenone, Paraquat, Piercidin A
393 • Nefazodone, Amiodarone, Flutamide, Benzbromarone, Metformin, Tolcapone, Entacapone, Diclofenac
394 Nefazodone, Amiodarone, Flutamide, Benzbromarone, Metformin, Tolcapone, Entacapone, Diclofenac
395 Antimycin A
  • Antimycin A, CAS-RN: 1397-94-0, DTXSID9032325
286, 287
396 Amiodarone, Benzbromarone
397 KCN
  • Potassium cyanide, CAS-RN: 151-50-8, DTXSID0024268
398 Nefazodone, Amiodarone, Benzbromarone, Metformin, Entacapone
399 Oligomycin A, Aurovertin
400 Nefazodone, Amiodarone, Metformin, Diclofenac
401 Valproic acid
  • Valproic acid, CAS-RN: 99-66-1, DTXSID6023733
274
402 Suberoylanilide hydroxamic acid
  • Suberoylanilide hydroxamic acid, CAS-RN: 149647-78-9, DTXSID6041133
274
403 MS-275
  • MS-275, CAS-RN: 209783-80-2, DTXSID0041068
274
404 Apicidin
  • Apicidin, CAS-RN: 183506-66-3, DTXSID40274182
274
405 p,p'-DDT
  • p,p'-DDT, CAS-RN: 50-29-3, DTXSID4020375
406 CITCO
  • CITCO, CAS-RN: 338404-52-7, DTXSID4040761
407 Epidermal growth factor
  • Epidermal growth factor, CAS-RN: 62229-50-9, DTXSID5040469
408 Epothilone A
  • Epothilone A, CAS-RN: 152044-53-6, DTXSID10332288
409 Epothilone B
  • Epothilone B, CAS-RN: 152044-54-7, DTXSID4046862
410 Paclitaxel
  • Paclitaxel, CAS-RN: 33069-62-4, DTXSID9023413
411 Zampanolide
412 Discodermolide
413 2,3-Pentanedione
  • 2,3-Pentanedione, CAS-RN: 600-14-6, DTXSID6051435
414 2,3-Butanedione
  • 2,3-Butanedione, CAS-RN: 431-03-8, DTXSID6021583
415 Light (290-700 nm)
282
416 Tunicamycin
  • Tunicamycin, CAS-RN: 11089-65-9, DTXSID8036730
417 Amphomycin
418 Fenpyroximate
  • Fenpyroximate, CAS-RN: 134098-61-6, DTXSID7032557
419 Pyridaben
  • Pyridaben, CAS-RN: 96489-71-3, DTXSID5032573
420 Benzbromarone
  • Benzbromarone, CAS-RN: 3562-84-3, DTXSID4022652
421 Nefazodone
  • Nefazodone, CAS-RN: 83366-66-9, DTXSID2023357
422 Metformin
  • Metformin, CAS-RN: 657-24-9, DTXSID2023270
423 Entacapone
  • Entacapone, CAS-RN: 130929-57-6, DTXSID5046439
424 Oligomycin
  • Oligomycin, CAS-RN: 1404-19-9, DTXSID7040570
425 Aurovertin
426 SC-839
427 Beta-carboline
428 BMS 345541
  • BMS 345541, CAS-RN: 547757-23-3, DTXSID70203243
429 Parthenolide
  • Parthenolide, CAS-RN: 20554-84-1, DTXSID2040579
430 Arsenite
  • Arsenite, CAS-RN: 15502-74-6, DTXSID0074007
263
431 Sulindac
  • Sulindac, CAS-RN: 38194-50-2, DTXSID4023624
432 Aspirin
  • Aspirin, CAS-RN: 50-78-2, DTXSID5020108
433 Phenethyl isothiocyanate
  • Phenethyl isothiocyanate, CAS-RN: 2257-09-2, DTXSID5021120
434 Sulforaphane
  • Sulforaphane, CAS-RN: 4478-93-7, DTXSID8036732
435 Dexamethosone, IL-1 receptor antagonist(IL-1Ra)(Anakinra), anti-IL-1b antibod (Canakinumab), soluble IL-1R (Rilonacept).
436 None
437 Dexamethosone, IL-1 receptor antagonist(IL-1Ra)(Anakinra), anti-IL-1b antibod (Canakinumab), soluble IL-1R (Rilonacept).
438 IL-1 receptor antagonist(IL-1Ra)(Anakinra), anti-IL-1b antibody (Canakinumab), soluble IL-1R (Rilonacept)
439 Chemical:20384 Dexamethasone, minocycline, innamicaldehyde
440 Photoreactive chemicals
282
441 finasteride, dutasteride, epristeride
289
442 5-Azacytidine
  • 5-Azacytidine, CAS-RN: 320-67-2, DTXSID9020116
290, 291, 336, 337, 338, 339, 340, 341
443 Decitabine
  • Decitabine, CAS-RN: 2353-33-5, DTXSID7030432
290, 291
444 Sinefungin
  • Sinefungin, CAS-RN: 58944-73-3, DTXSID10207689
290, 291
445 Psammaplin A
290, 291
446 Hydralazine hydrochloride
  • Hydralazine hydrochloride, CAS-RN: 304-20-1, DTXSID1044645
290, 291
447 Zebularine
290, 291
448 RG 108
290, 291
449 Temozolomide
  • Temozolomide, CAS-RN: 85622-93-1, DTXSID5043714
290, 291
450 1-phenyl 2-thiourea
292
451 Ionizing Radiation
293, 294, 296, 272, 298, 216, 238, 386, 387, 388, 299, 396, 432, 441
452 Estrogen
453 Other DNA damaging agents
294, 293
454 Hydrogen peroxide
  • Hydrogen peroxide, CAS-RN: 7722-84-1, DTXSID2020715
296
455 Potassium bromate
  • Potassium bromate, CAS-RN: 7758-01-2, DTXSID6020195
296
456 Cadmium chloride
  • Cadmium chloride, CAS-RN: 10108-64-2, DTXSID6020226
296
457 tert-Butyl hydroperoxide
  • tert-Butyl hydroperoxide, CAS-RN: 75-91-2, DTXSID9024693
296
458 Sodium arsenite
  • Sodium arsenite, CAS-RN: 7784-46-5, DTXSID5020104
459 Topoisomerase inhibitors
460 Radiomimetic compounds
461 Disulphiram
297
462 Diethylaminobenzaldehyde
297
463 Citral
297
464 Paclobutrazol
  • Paclobutrazol, CAS-RN: 76738-62-0, DTXSID2024242
297
465 nitrofen
  • Nitrofen, CAS-RN: 1836-75-5, DTXSID7020970
297, 436
466 4-biphenyl carboxylic acid
297
467 Bisdiamine
297, 436
468 SB-210661
297
469 Vinblastine sulfate
  • Vinblastine sulfate, CAS-RN: 18556-44-0, DTXSID7047853
106
470 Wnt
298
471 WNT2
298
472 WNT5A
473 CHIR99021
474 BIO (6-bromoindirubin-3’-oxime)
410
475 Kenpaullone
476 SB216763
477 TWS119
  • TWS119, CAS-RN: 601514-19-6, DTXSID00429550
478 CHIR98014
479 Wnt ligand
480 CHIR-99021
  • CHIR-99021, CAS-RN: 252917-06-9, DTXSID90179931
481 CHIR-98014
482 GOLPH3
483 LiCl
484 D-2-hydroxyglutarate
485 Dexamethosone
486 minocycline
  • Minocycline, CAS-RN: 10118-90-8, DTXSID1045033
277
487 Pralnacasan (VX-740) and Belnacasan (VX-765)
488 cinnamic aldehyde
277
489 IL-1 receptor antagonist(IL-1Ra)(Anakinra)
277
490 anti-IL-1b antibody (Canakinumab)
277
491 soluble IL-1R (Rilonacept)
277
492 Dexamethasone
  • Dexamethasone, CAS-RN: 50-02-2, DTXSID3020384
277
493 Aminooxyacetic acid
  • Aminooxyacetic acid, CAS-RN: 645-88-5, DTXSID50214756
301
494 S-(4-Carboxybutyl)-D,L-homocysteine; 5-(3-Amino-3-carboxypropyl)sulfanyl-pentanoic acid
301
495 Stressor:488 cinnamic aldehyde
496 Stressor:491 soluble IL-1R (Rilonacept)
497 Stressor:492 Dexamethasone
498 Sunlight (wavelength: 290-700 nm)
499 Photoactivated chemicals
500 High aspect ratio material
303
501 acrylamio
502 Low LET Radiation
503 High LET Ra
504 High LET Radiation
505 Progesterone,estrogen,melatonin,Letrozole
309
506 glucocorticoids
309
507 Cetrorelix
  • Cetrorelix, CAS-RN: 120287-85-6, DTXSID7040996
309
508 Interleukin-6
  • Interleukin-6, CAS-RN: NOCAS_41050, DTXSID6041050
309
509 benzo[a]pyrene
310
510 colchemid
511 Colcemid
  • Colcemid, CAS-RN: 477-30-5, DTXSID7020342
512 2-Methoxyestradiol
  • 2-Methoxyestradiol, CAS-RN: 362-07-2, DTXSID3040938
513 Podophyllotoxin
514 Hydroquinone
  • Hydroquinone, CAS-RN: 123-31-9, DTXSID7020716
296
515 4-Nitroquinoline 1-oxide
296
516 oxidative stress
517 Gevokizumab
518 anti-IL-1b antibody (Gevokizumab)
277
519 Imiquimod
  • Imiquimod, CAS-RN: 99011-02-6, DTXSID7041047
313
520 Resiquimod
  • Resiquimod, CAS-RN: 144875-48-9, DTXSID7040603
313
521 Bisphenol A
  • Bisphenol A, CAS-RN: 80-05-7, DTXSID7020182
314
522 Porcupine
298
523 Wntless
298
524 testJF
525 testJF2
526 SARS-CoV
320, 377, 430
527 COVID-19
528 PM 2.5
319
529 Pimecrolimus
  • Pimecrolimus, CAS-RN: 137071-32-0, DTXSID2046674
154
530 Gossypol
  • Gossypol, CAS-RN: 303-45-7, DTXSID5023110
154
531 Kaempferol
  • Kaempferol, CAS-RN: 520-18-3, DTXSID7020768
154
532 Dodecylbenzene sulfonate
154
533 Dibefurin
154
534 Ascomycin
154
535 1,5-dibenzoyloxymethyl-norcantharidin
154
536 Azathioprine
  • Azathioprine, CAS-RN: 446-86-6, DTXSID4020119
537 Methotrexate
  • Methotrexate, CAS-RN: 59-05-2, DTXSID4020822
538 Benzo(a)pyrene
  • Benzo(a)pyrene, CAS-RN: 50-32-8, DTXSID2020139
539 Urethane
  • Urethane, CAS-RN: 51-79-6, DTXSID9021427
540 1,2:5,6-dibenzanthracene
541 psychosocial stress
403
542 Radiation
543 beta-Sitosterol
  • beta-Sitosterol, CAS-RN: 83-46-5, DTXSID5022481
544 Abamectin
  • Abamectin, CAS-RN: 71751-41-2, DTXSID8023892
545 Carbenoxolone
  • Carbenoxolone, CAS-RN: 5697-56-3, DTXSID4022733
348
546 Malathion
  • Malathion, CAS-RN: 121-75-5, DTXSID4020791
547 Dimethoate
  • Dimethoate, CAS-RN: 60-51-5, DTXSID7020479
548 Triphenyl phosphate
  • Triphenyl phosphate, CAS-RN: 115-86-6, DTXSID1021952
393, 401
549 Atorvastatin
  • Atorvastatin, CAS-RN: 134523-00-5, DTXSID8029868
550 Streptozocin
319
551 Losartan
  • Losartan, CAS-RN: 114798-26-4, DTXSID7023227
319
552 furan
  • Furan, CAS-RN: 110-00-9, DTXSID6020646
553 acetone
  • Acetone, CAS-RN: 67-64-1, DTXSID8021482
554 too many stressors to list
555 Simvastatin
  • Simvastatin, CAS-RN: 79902-63-9, DTXSID0023581
556 Vinclozolin
  • Vinclozolin, CAS-RN: 50471-44-8, DTXSID4022361
557 Triticonazole
  • Triticonazole, CAS-RN: 131983-72-7, DTXSID0032655
558 Flusilazole
  • Flusilazole, CAS-RN: 85509-19-9, DTXSID3024235
559 Epoxiconazole
  • Epoxiconazole, CAS-RN: 133855-98-8, DTXSID1040372
560 Cyproterone acetate
  • Cyproterone acetate, CAS-RN: 427-51-0, DTXSID5020366
561 Butylparaben
  • Butylparaben, CAS-RN: 94-26-8, DTXSID3020209
562 p,p'-DDE
  • p,p'-DDE, CAS-RN: 72-55-9, DTXSID9020374
563 Fenitrothion
  • Fenitrothion, CAS-RN: 122-14-5, DTXSID4032613
564 Linuron
  • Linuron, CAS-RN: 330-55-2, DTXSID2024163
565 Procymidone
  • Procymidone, CAS-RN: 32809-16-8, DTXSID9033923
566 di-n-hexyl phthalate
567 Dicyclohexyl phthalate
  • Dicyclohexyl phthalate, CAS-RN: 84-61-7, DTXSID5025021
568 butyl benzyl phthalate
569 monobenzyl phthalate
570 di-n-heptyl phthalate
571 ferric nitrilotriacetate
298
572 N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide
348
573 Beclomethasone dipropionate monohydrate
  • Beclomethasone dipropionate monohydrate, CAS-RN: 77011-63-3, DTXSID00227831
334
574 Metyrapone
  • Metyrapone, CAS-RN: 54-36-4, DTXSID1023314
349
575 Lysodren, Mitotan, Mitotane
  • Lysodren, Mitotan, Mitotane, CAS-RN: 164203-73-0, DTXSID30425146
349
576 Etomidate
  • Etomidate, CAS-RN: 33125-97-2, DTXSID5023033
349
577 Osilodrostat(LCI699)
349
578 Glycyrrhizin
  • Glycyrrhizin, CAS-RN: 1405-86-3, DTXSID8047006
348
579 PF915275
348
580 Bicalutamide
  • Bicalutamide, CAS-RN: 90357-06-5, DTXSID2022678
581 Stressor:286 Tebuconazole
582 Propylpyrazoletriol
583 4-Hydroxytamoxifen
  • 4-Hydroxytamoxifen, CAS-RN: 68392-35-8, DTXSID3037094
584 Stressor:48 Propylthiouracil
585 PF-06651600 (CAS No:1792180-81-4),
315
586 RB1
315
587 PF-06651600 (CAS No:1792180-81-4), RB1
588 Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide Pimozide
589 Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide
590 Tofacitinib (CP690,550)
591 Cyclosporin, FK506, Basiliximab, PFOA (perfluorooctanoic acid)
593 Polyoxin D
360
594 Captafol
  • Captafol, CAS-RN: 2425-06-1, DTXSID4020242
360
595 Captan
  • Captan, CAS-RN: 133-06-2, DTXSID9020243
360
596 Folpet
  • Folpet, CAS-RN: 133-07-3, DTXSID0021385
360
597 Capta
598 Exemestane
  • Exemestane, CAS-RN: 107868-30-4, DTXSID5023037
346
599 Stressor:292 Clotrimazole
346
600 Pentachlorophenol
  • Pentachlorophenol, CAS-RN: 87-86-5, DTXSID7021106
263
601 Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
263
602 Carbonyl cyanide m-chlorophenyl hydrazone
263
603 Triclosan
  • Triclosan, CAS-RN: 3380-34-5, DTXSID5032498
263
604 Dinoseb
  • Dinoseb, CAS-RN: 88-85-7, DTXSID3020207
263
605 Emodin
  • Emodin, CAS-RN: 518-82-1, DTXSID5025231
263
606 Malonoben
  • Malonoben, CAS-RN: 10537-47-0, DTXSID1042106
607 Stressor:205 pirinixic acid (WY-14,643)
608 Pralnacasan (VX-740)
609 Belnacasan (VX-765)
277
610 HMR3480
611 Pralnacasan (VX-740, HMR3480)
277
612 curcumin
  • Curcumin, CAS-RN: 458-37-7, DTXSID8031077
277
613 inguratimod
614 iguratimod
  • Iguratimod, CAS-RN: 123663-49-0, DTXSID0048971
277
615 epigallocathechin gallate
616 TAK-242
277
617 IRAK4 inhibitors
277
618 Wy-14,6423
619 SARS-CoV and CoV-NL63, SARS-CoV
620 HCoV-NL63
320, 430
621 DX600
319
622 cationic polyamidoamine dendrimer (nanoparticle)
319
623 Hy
624 Sars-CoV-2
374, 377, 320, 392, 422, 430
625 bacteria
374
626 fungi
627 Dummy Stressor
628 cell free mitochondrial DNA (mtDNA)
377
629 unmethylated CpG motifs (DNA;RNA;ODN)
377
630 Chemical:33664 17-Methyltestosterone
376
631 Danger Associated Molecular Patters (DAMPs)
377
632 Pathogen Associated Molecular Patterns (PAMPs)
377
633 Stressor:624 SARS-CoV-2
379
634 nanomaterials
635 Arsenic
  • Arsenic, CAS-RN: 7440-38-2, DTXSID4023886
413
636 Dehydroxymethylepoxyquinomicin (DHMEQ)
277
637 Dimethyl fumarate
277
638 (-)-Epigallocatechin gallate
  • (-)-Epigallocatechin gallate, CAS-RN: 989-51-5, DTXSID1029889
277
639 Methyldihydrotestosterone
376
640 11-Keto-testosterone
  • 11-Keto-testosterone, CAS-RN: 564-35-2, DTXSID8036499
376
641 Rosmarinic acid
399
642 Saracatinib
  • Saracatinib, CAS-RN: 379231-04-6, DTXSID90191355
399
643 Staurosporine
  • Staurosporine, CAS-RN: 62996-74-1, DTXSID6041131
399
644 Rocilinostat / Ricolinostat
645 Cigarette smoke
  • Cigarette smoke, CAS-RN: NOCAS_35038, DTXSID5035038
403, 411, 424, 425
646 high fat diet
403
647 physical inactivity
403
648 work stress
403
649 Paraoxon
  • Paraoxon, CAS-RN: 311-45-5, DTXSID6024046
405, 450
650 Methyl parathion
  • Methyl parathion, CAS-RN: 298-00-0, DTXSID1020855
405, 450
651 Ethyl Parathion
405, 450
652 Retinoic acid
653 su5402
  • su5402, CAS-RN: 215543-92-3, DTXSID90415361
654 Stressor:454 Hydrogen peroxide
655 Ozone
  • Ozone, CAS-RN: 10028-15-6, DTXSID0021098
411, 424
656 Acetaldehyde
  • Acetaldehyde, CAS-RN: 75-07-0, DTXSID5039224
657 Nicotine
  • Nicotine, CAS-RN: 54-11-5, DTXSID1020930
658 Sulfur dioxide
  • Sulfur dioxide, CAS-RN: 7446-09-5, DTXSID6029672
659 Formaldehyde
  • Formaldehyde, CAS-RN: 50-00-0, DTXSID7020637
660 PM10
661 Nitric oxide
  • Nitric oxide, CAS-RN: 10102-43-9, DTXSID1020938
662 Irradiation
663 Stressor:645 Cigarette smoke
664 Uranium
  • Uranium, CAS-RN: 7440-61-1, DTXSID1042522
413, 447
665 Bis(2,4,6-trimethylphenyl)-lambda~2~-germane--selenium (1/1)
  • Bis(2,4,6-trimethylphenyl)-lambda~2~-germane--selenium (1/1), CAS-RN: 115385-04-1, DTXSID10556604
413
666 Ammonia
  • Ammonia, CAS-RN: 7664-41-7, DTXSID0023872
667 Diesel engine exhaust
  • Diesel engine exhaust, CAS-RN: NOCAS_24043, DTXSID1024043
411, 451
668 Wood smoke
669 Mycotoxin
  • Mycotoxin, CAS-RN: NOCAS_40884, DTXSID0040884
670 1,2,5,6,9,10-Hexabromocyclododecane
  • 1,2,5,6,9,10-Hexabromocyclododecane, CAS-RN: 3194-55-6, DTXSID4027527
671 Asbestos fibers
  • Asbestos fibers, CAS-RN: NOCAS_30740, DTXSID0030740
409
672 Food deprivation
  • Food deprivation, CAS-RN: NOCAS_35060, DTXSID7035060
673 Nitrogen dioxide
  • Nitrogen dioxide, CAS-RN: 10102-44-0, DTXSID7020974
411
674 Sex hormone
675 Heavy metals (cadmium, lead, copper, iron, nickel)
676 Mitochondrial ETC inhibitors
677 Serum
  • Serum, CAS-RN: NOCAS_41123, DTXSID2041123
678 Impregnation products
679 Meconium
680 Cholesterol
  • Cholesterol, CAS-RN: 57-88-5, DTXSID3022401
681 Prototypical stressor
211
682 WIN18,466
683 (~13~C,~15~N_2_)Cyanamide
  • (~13~C,~15~N_2_)Cyanamide, CAS-RN: 87009-57-2, DTXSID90745933
684 Molinate
  • Molinate, CAS-RN: 2212-67-1, DTXSID6024206
685 Pebulate
  • Pebulate, CAS-RN: 1114-71-2, DTXSID8021199
686 Vernolate
  • Vernolate, CAS-RN: 1929-77-7, DTXSID7024376
687 Butylate
  • Butylate, CAS-RN: 2008-41-5, DTXSID7023936
688 Tri-allate
  • Tri-allate, CAS-RN: 2303-17-5, DTXSID5024344
689 Cycloate
  • Cycloate, CAS-RN: 1134-23-2, DTXSID6032356
690 Itraconazole
  • Itraconazole, CAS-RN: 84625-61-6, DTXSID3023180
691 Candesartan cilexetil
  • Candesartan cilexetil, CAS-RN: 145040-37-5, DTXSID5020239
692 Montelukast
  • Montelukast, CAS-RN: 158966-92-8, DTXSID9023334
693 Repaglinide
  • Repaglinide, CAS-RN: 135062-02-1, DTXSID3023552
694 Liarozole
  • Liarozole, CAS-RN: 115575-11-6, DTXSID9048277
695 (R)-Talarozole
  • (R)-Talarozole, CAS-RN: 870093-23-5, DTXSID50236074
696 Stressor:282 Ketoconazole
697 all-trans-Retinoic acid
  • all-trans-Retinoic acid, CAS-RN: 302-79-4, DTXSID7021239
698 Diethylhexyl phthalate
431
699 Influenza Virus
700 Escitalopram
  • Escitalopram, CAS-RN: 128196-01-0, DTXSID8048440
701 Astemizole
  • Astemizole, CAS-RN: 68844-77-9, DTXSID9020110
702 Probucol
  • Probucol, CAS-RN: 23288-49-5, DTXSID2045440
703 Quinidine
  • Quinidine, CAS-RN: 56-54-2, DTXSID4023549
704 Disopyramide
  • Disopyramide, CAS-RN: 3737-09-5, DTXSID1045536
705 Procainamide
  • Procainamide, CAS-RN: 51-06-9, DTXSID7023512
706 Terfenadine
  • Terfenadine, CAS-RN: 50679-08-8, DTXSID2023642
707 Cisapride
  • Cisapride, CAS-RN: 81098-60-4, DTXSID3022825
708 Tetraarsenic trioxide
  • Tetraarsenic trioxide, CAS-RN: 83527-54-2, DTXSID80232428
709 Pentamidine
  • Pentamidine, CAS-RN: 100-33-4, DTXSID7023431
710 Geldanamycin
  • Geldanamycin, CAS-RN: NOCAS_42691, DTXSID7042691
711 Silver
  • Silver, CAS-RN: 7440-22-4, DTXSID4024305
712 Gold nanoparticles
713 Chromium
  • Chromium, CAS-RN: 7440-47-3, DTXSID3031022
714 Other heavy metal effects
715 Other heavy metals
716 Cisplatin
  • Cisplatin, CAS-RN: 15663-27-1, DTXSID4024983
717 Nanoparticles and Micrometer Particles
718 Platinum
719 2) Aluminum
720 Aluminum
  • Aluminum, CAS-RN: 7429-90-5, DTXSID3040273
721 Manganese
  • Manganese, CAS-RN: 7439-96-5, DTXSID2024169
722 Nickel
  • Nickel, CAS-RN: 7440-02-0, DTXSID2020925
723 Zinc
  • Zinc, CAS-RN: 7440-66-6, DTXSID7035012
724 Gold
  • Gold, CAS-RN: 7440-57-5, DTXSID3064697
725 All-trans retinoic acid
726 BMS-89453
436
727 WIN18446
728 4-diethylaminobenzaldehyde (DEAB)
436
729 WIN18466
436
730 a
731 All-trans retionic acid
436
732 Vitamin A
436
733 Nanoparticles and micrometer
734 Clomiphene citrate (1:1)
  • Clomiphene citrate (1:1), CAS-RN: 50-41-9, DTXSID8020337
440
735 Clomiphene
  • Clomiphene, CAS-RN: 911-45-5, DTXSID1022843
736 Tamoxifen epoxide
  • Tamoxifen epoxide, CAS-RN: 92137-93-4, DTXSID40238885
737 Ethyl alcohol
443
738 Uranium, soluble salts
  • Uranium, soluble salts, CAS-RN: NOCAS_24374, DTXSID7024374
447
739 welding fumes
451
740 Carbon black
  • Carbon black, CAS-RN: 1333-86-4, DTXSID7051216
451
741 DCA
335
742 DCPMU
335
743 Niclosamide ethanolamine
263
744 Oxyclozanide
  • Oxyclozanide, CAS-RN: 2277-92-1, DTXSID50177312
263
745 Fumonisin B1
  • Fumonisin B1, CAS-RN: 116355-83-0, DTXSID6020644
449
746 Vismodegib
  • Vismodegib, CAS-RN: 879085-55-9, DTXSID40236689
460
747 Toluene diisocyanate
  • Toluene diisocyanate, CAS-RN: 26471-62-5, DTXSID0024341
39
748 Cyclopamine
  • Cyclopamine, CAS-RN: 4449-51-8, DTXSID6043709
460