API

Stressor: 296

Title

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>85 known Cyp2E1 substrates

Stressor Overview

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AOPs Including This Stressor

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Events Including This Stressor

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Chemical Table

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AOP Evidence

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Chronic Cyp2E1 Activation Leading to Liver Cancer

Low molecular weight compounds, including: molecular oxygen, acetone, acetaminophen, carbon tetrachloride, pyrazole, vinyl chloride, furan, chloroform, ethanol, benzene, acrylonitrile, trichloroethylene, aniline, N-nitrosodimethylamine, N-nitrosodiethylamine, diethylnitrosamine,   thioacetamide, and toluene. A variety of substrates have been described (Lieber 1997, Tanaka, et al. 2000).




Event Evidence

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This table is automatically generated and includes the Events with this associated stressor as well as the evidence text from this Event Stressor.



Stressor Info

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Chemical/Category Description

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Characterization of Exposure

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References

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