API

Relationship: 1090

Title

?

Increased, secrection of FSH from anterior pituitary leads to Hyperplasia, ovarian stromal cells

Upstream event

?

Increased, secrection of FSH from anterior pituitary

Downstream event

?


Hyperplasia, ovarian stromal cells

Key Event Relationship Overview

?


AOPs Referencing Relationship

?

AOP Name Adjacency Weight of Evidence Quantitative Understanding
Antiestrogen activity leading to ovarian adenomas and granular cell tumors in the mouse non-adjacent Moderate

Taxonomic Applicability

?

Sex Applicability

?

Life Stage Applicability

?

Key Event Relationship Description

?


Evidence Supporting this KER

?


Biological Plausibility

?

Empirical Evidence

?

Uncertainties and Inconsistencies

?

Quantitative Understanding of the Linkage

?


Response-response Relationship

?

Time-scale

?

Known modulating factors

?

Known Feedforward/Feedback loops influencing this KER

?

Domain of Applicability

?


References

?