Relationship: 1129
Title
Increased, secretion of local growth factors leads to Increased, Cell Proliferation (mesothelium)
Upstream event
Increased, secretion of local growth factorsDownstream event
Increased, Cell Proliferation (mesothelium)
Key Event Relationship Overview
AOPs Referencing Relationship
| AOP Name | Directness | Weight of Evidence | Quantitative Understanding |
|---|---|---|---|
| Chronic cytotoxicity of the serous membrane leading to pleural/peritoneal mesotheliomas in the rat. | directly leads to | Strong |