API

Relationship: 398

Title

?

Increase proliferation, Leydig cell leads to Hyperplasia, Leydig cell

Upstream event

?

Increase proliferation, Leydig cell

Downstream event

?


Hyperplasia, Leydig cell

Key Event Relationship Overview

?


AOPs Referencing Relationship

?

AOP Name Directness Weight of Evidence Quantitative Understanding
PPARα activation leading to impaired fertility in adult male rodents directly leads to Moderate

Taxonomic Applicability

?


Sex Applicability

?


Life Stage Applicability

?


How Does This Key Event Relationship Work

?


Weight of Evidence

?


Biological Plausibility

?

Empirical Support for Linkage

?

Uncertainties or Inconsistencies

?

Quantitative Understanding of the Linkage

?


Evidence Supporting Taxonomic Applicability

?


References

?