API XML

Aop: 52

AOP Title

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ER agonism leading to skewed sex ratios due to altered sexual differentiation in males

Short name:

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ER agonism : Skewed sex ratios

Graphical Representation

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Click to download graphical representation template

Authors

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  • Professor Tom Hutchinson, School of Biological Sciences, Plymouth, UK [tom.hutchinson{at}plymouth.ac.uk]
  • Dan Villeneuve, US EPA Mid-Continent Ecology Division, Duluth, MN. [villeneuve.dan{at}epa.gov]

Point of Contact

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Tom Hutchinson   (email point of contact)

Contributors

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  • Tom Hutchinson

Status

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Author status OECD status OECD project SAAOP status
Under development: Not open for comment. Do not cite 1.29 Under Development


This AOP was last modified on January 27, 2018 15:34

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Revision dates for related pages

Page Revision Date/Time
Agonism, Estrogen receptor September 16, 2017 10:14
skewed, sex ratio December 03, 2016 16:37

Abstract

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Background (optional)

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Summary of the AOP

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Events: Molecular Initiating Events (MIE)

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Key Events (KE)

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Adverse Outcomes (AO)

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Sequence Type Event ID Title Short name
1 MIE 111 Agonism, Estrogen receptor Agonism, Estrogen receptor
2 AO 417 skewed, sex ratio skewed, sex ratio

Relationships Between Two Key Events
(Including MIEs and AOs)

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Network View

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Stressors

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Life Stage Applicability

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Taxonomic Applicability

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Sex Applicability

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Overall Assessment of the AOP

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Domain of Applicability

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Essentiality of the Key Events

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Evidence Assessment

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Quantitative Understanding

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Considerations for Potential Applications of the AOP (optional)

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References

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