API

Event: 1491

Key Event Title

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Increased, Oncotic Necrosis

Short name

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increased, oncotic necrosis

Biological Context

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Level of Biological Organization
Tissue


Organ term

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Key Event Components

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Process Object Action

Key Event Overview


AOPs Including This Key Event

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Stressors

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Taxonomic Applicability

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Life Stages

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Life stage Evidence
All life stages High

Sex Applicability

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Term Evidence
Unspecific High

Key Event Description

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Biological state: cell death resulting from cellular swelling, as opposed to apoptosis.

Biological compartment: tissue level -- cellular swelling and death.

General role in biology: oncotic necrosis is cell death that is not planned or programmed. Oncotic necrosis typically results in inflammation.


How It Is Measured or Detected

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Typically using plasma membrane permeability.


Domain of Applicability

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Known to occur in most eukaryotes.


References

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