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Key Event Title
olfactory sensory neurons, decrease
Key Event Components
Key Event Overview
AOPs Including This Key Event
Key Event Description
Biological state: The olfactory sensory neurons (OSNs) together with a number nonneuronal cells form the olfactory epithelium (OE). They are bipolar neuronal cells. The dendritic end of the OSNs is exposed to the nasal mucus, whereas their axonal pole is synaptically connected to the olfactory bulb of the central nervous system (CNS) (Liang, 2020). OSNs in the OE could be differentiated into hundreds of subsets, depending on the phenotype of odorant receptor proteins.
Biological compartment: The OSNs are located in the olfactory epithelium (OE).
General role in the biology: The OSNs are the OE’s parenchymal cells responsible for olfactory reception and transduction. The OSNs project their axons via the olfactory nerve onto the olfactory bulb. The OSNs are undoubtedly the OE’s parenchymal cells responsible for olfactory reception and transduction.
How It Is Measured or Detected
Domain of Applicability
Liang F. Sustentacular Cell Enwrapment of Olfactory Receptor Neuronal Dendrites: An Update. Genes (Basel). 2020 Apr 30;11(5):493. doi: 10.3390/genes11050493. PMID: 32365880; PMCID: PMC7291085.